| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Baker Mayfield | QB | TB | 29 | Week 11 | ||
| Tua Tagovailoa | QB | Mia | 26 | No More Bye | ||
| Trevor Lawrence | QB | Jac | 25 | Week 12 | Questionable | Shoulder |
| James Cook | RB | Buf | 25 | Week 12 | ||
| Jaylen Warren | RB | Pit | 26 | No More Bye | ||
| Nick Chubb | RB | Cle | 28 | Week 10 | ||
| James Conner | RB | Ari | 29 | Week 11 | ||
| Kimani Vidal | RB | LAC | 23 | No More Bye | ||
| Brian Thomas Jr. | WR | Jac | 22 | Week 12 | Questionable | Chest |
| Marvin Harrison Jr. | WR | Ari | 22 | Week 11 | ||
| Calvin Ridley | WR | Ten | 29 | No More Bye | ||
| Christian Kirk | WR | Jac | 27 | Week 12 | NFI | Collarbone |
| Josh Downs | WR | Ind | 23 | Week 14 | ||
| Amon-Ra St. Brown | WR | Det | 25 | No More Bye | ||
| David Njoku | TE | Cle | 28 | Week 10 | ||
| Zach Ertz | TE | Was | 33 | Week 14 | ||
| Ben Sinnott | TE | Was | 22 | Week 14 | ||
| Austin Seibert | PK | Was | 27 | Week 14 | Questionable | Hip |
| Harold Landry | DL | Ten | 28 | No More Bye | ||
| Jared Verse | DL | LAR | 24 | No More Bye | ||
| Danielle Hunter | DL | Hou | 30 | Week 14 | ||
| DeForest Buckner | DL | Ind | 30 | Week 14 | ||
| Matt Judon | DL | Atl | 32 | Week 12 | ||
| Edgerrin Cooper | LB | GB | 22 | Week 10 | ||
| Patrick Queen | LB | Pit | 25 | No More Bye | ||
| Fred Warner | LB | SF | 27 | No More Bye | ||
| Kyzir White | LB | Ari | 28 | Week 11 | ||
| Germaine Pratt | LB | Cin | 28 | Week 12 | ||
| Nick Bolton | LB | KC | 24 | No More Bye | ||
| Marlon Humphrey | CB | Bal | 28 | Week 14 | ||
| Kenny Moore | CB | Ind | 29 | Week 14 | ||
| Budda Baker | S | Ari | 28 | Week 11 | ||
| Derwin James | S | LAC | 28 | No More Bye |