| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Baker Mayfield | QB | TB | 29 | Week 11 | ||
| Sam Darnold | QB | Min | 27 | Week 6 | ||
| Aaron Rodgers | QB | NYJ | 40 | Week 12 | ||
| Jaleel McLaughlin | RB | Den | 24 | Week 14 | ||
| Emanuel Wilson | RB | GB | 25 | Week 10 | ||
| Zamir White | RB | LV | 25 | Week 10 | ||
| De'Von Achane | RB | Mia | 22 | Week 6 | ||
| Ray Davis | RB | Buf | 24 | Week 12 | ||
| Audric Estime | RB | Den | 21 | Week 14 | NFI | Ankle |
| Rhamondre Stevenson | RB | NE | 26 | Week 14 | ||
| Michael Pittman | WR | Ind | 26 | Week 14 | ||
| Josh Palmer | WR | LAC | 24 | Week 5 | Questionable | Calf |
| CeeDee Lamb | WR | Dal | 25 | Week 7 | Questionable | Ankle |
| Ray-Ray McCloud | WR | Atl | 27 | Week 12 | ||
| Demario Douglas | WR | NE | 23 | Week 14 | ||
| Jaxon Smith-Njigba | WR | Sea | 22 | Week 10 | ||
| Chris Olave | WR | NO | 24 | Week 12 | ||
| Jake Ferguson | TE | Dal | 25 | Week 7 | Questionable | Knee - MCL |
| Taysom Hill | TE | NO | 34 | Week 12 | Questionable | Chest |
| Ka'imi Fairbairn | PK | Hou | 30 | Week 14 | ||
| Blake Grupe | PK | NO | 25 | Week 12 | ||
| Aidan Hutchinson | DL | Det | 24 | Week 5 | ||
| Myles Garrett | DL | Cle | 28 | Week 10 | Questionable | Foot |
| Montez Sweat | DL | Chi | 28 | Week 7 | Questionable | Elbow |
| Demarcus Lawrence | DL | Dal | 32 | Week 7 | ||
| Jordyn Brooks | LB | Mia | 26 | Week 6 | ||
| Patrick Queen | LB | Pit | 25 | Week 9 | ||
| E.J. Speed | LB | Ind | 29 | Week 14 | ||
| Azeez Al-Shaair | LB | Hou | 27 | Week 14 | Questionable | Shin |
| Darius Slay | CB | Phi | 33 | Week 5 | ||
| Devon Witherspoon | CB | Sea | 23 | Week 10 | Questionable | Hamstring |
| Nick Cross | S | Ind | N/A | Week 14 | ||
| Camryn Bynum | S | Min | 26 | Week 6 |