| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Bo Nix | QB | Den | 24 | Week 14 | ||
| Daniel Jones | QB | NYG | 27 | Week 11 | ||
| C.J. Stroud | QB | Hou | 22 | Week 14 | ||
| David Montgomery | RB | Det | 27 | Week 5 | ||
| Tony Pollard | RB | Ten | 27 | Week 5 | ||
| Jonathan Taylor | RB | Ind | 25 | Week 14 | ||
| Travis Etienne | RB | Jac | 25 | Week 12 | ||
| Nick Chubb | RB | Cle | 28 | Week 10 | PUP | Knee - ACL + MCL |
| Dalvin Cook | RB | Dal | 29 | Week 7 | ||
| D'Onta Foreman | RB | Cle | 28 | Week 10 | ||
| Demarcus Robinson | WR | LAR | 29 | Week 6 | ||
| Brandin Cooks | WR | Dal | 30 | Week 7 | ||
| Amari Cooper | WR | Cle | 30 | Week 10 | ||
| Christian Watson | WR | GB | 25 | Week 10 | ||
| Darius Slayton | WR | NYG | 27 | Week 11 | ||
| Rashee Rice | WR | KC | 24 | Week 6 | ||
| Gabriel Davis | WR | Jac | 25 | Week 12 | ||
| Sam LaPorta | TE | Det | 23 | Week 5 | ||
| Cole Kmet | TE | Chi | 25 | Week 7 | ||
| Ka'imi Fairbairn | PK | Hou | 30 | Week 14 | ||
| Leonard Williams | DL | Sea | 30 | Week 10 | Questionable | Knee |
| Danielle Hunter | DL | Hou | 29 | Week 14 | ||
| DeForest Buckner | DL | Ind | 30 | Week 14 | NFI | Ankle |
| Christian Wilkins | DL | LV | 28 | Week 10 | Questionable | Knee |
| Germaine Pratt | LB | Cin | 28 | Week 12 | ||
| Demario Davis | LB | NO | 35 | Week 12 | ||
| T.J. Edwards | LB | Chi | 28 | Week 7 | ||
| Patrick Queen | LB | Pit | 25 | Week 9 | ||
| Ivan Pace | LB | Min | 23 | Week 6 | Questionable | Quadriceps |
| Taron Johnson | CB | Buf | 28 | Week 12 | Out | Forearm |
| Kenny Moore | CB | Ind | 29 | Week 14 | ||
| Derwin James | S | LAC | 28 | Week 5 | ||
| Kevin Byard | S | Chi | 31 | Week 7 |