| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Caleb Williams | QB | Chi | 22 | Week 7 | ||
| Lamar Jackson | QB | Bal | 27 | Week 14 | ||
| Anthony Richardson | QB | Ind | 22 | Week 14 | ||
| Zach Charbonnet | RB | Sea | 23 | Week 10 | ||
| Kendre Miller | RB | NO | 22 | Week 12 | NFI | Hamstring |
| Emanuel Wilson | RB | GB | 25 | Week 10 | ||
| Tyler Allgeier | RB | Atl | 24 | Week 12 | Questionable | Hip |
| Jaylen Warren | RB | Pit | 25 | Week 9 | ||
| Audric Estime | RB | Den | 21 | Week 14 | NFI | Ankle |
| Keenan Allen | WR | Chi | 32 | Week 7 | Questionable | Heel |
| Adam Thielen | WR | Car | 34 | Week 11 | ||
| Mike Evans | WR | TB | 31 | Week 11 | ||
| Jaylen Waddle | WR | Mia | 25 | Week 6 | ||
| Amon-Ra St. Brown | WR | Det | 24 | Week 5 | ||
| Drake London | WR | Atl | 24 | Week 12 | ||
| A.T. Perry | WR | NO | 24 | Week 12 | ||
| Trey McBride | TE | Ari | 24 | Week 11 | ||
| Greg Dulcich | TE | Den | 24 | Week 14 | Questionable | Knee |
| Taysom Hill | TE | NO | 34 | Week 12 | Questionable | Chest |
| Tyler Bass | PK | Buf | 27 | Week 12 | ||
| Jonathan Greenard | DL | Min | 27 | Week 6 | ||
| Montez Sweat | DL | Chi | 28 | Week 7 | Questionable | Elbow |
| Trey Hendrickson | DL | Cin | 29 | Week 12 | ||
| Jared Verse | DL | LAR | 23 | Week 6 | ||
| Shaq Thompson | LB | Car | 30 | Week 11 | ||
| Azeez Al-Shaair | LB | Hou | 27 | Week 14 | Questionable | Shin |
| Devin White | LB | Phi | 26 | Week 5 | ||
| Nick Bolton | LB | KC | 24 | Week 6 | ||
| Henry To'oTo'o | LB | Hou | N/A | Week 14 | ||
| Nate Hobbs | CB | LV | 25 | Week 10 | ||
| Paulson Adebo | CB | NO | 24 | Week 12 | ||
| Budda Baker | S | Ari | 28 | Week 11 | ||
| Jaquan Brisker | S | Chi | 25 | Week 7 |