| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Geno Smith | QB | Sea | 34 | No More Bye | ||
| Justin Herbert | QB | LAC | 26 | No More Bye | ||
| Will Shipley | RB | Phi | 22 | No More Bye | ||
| Trey Sermon | RB | Ind | 25 | Week 14 | ||
| Kyle Juszczyk | RB | SF | 33 | No More Bye | ||
| Alvin Kamara | RB | NO | 29 | Week 12 | ||
| Dare Ogunbowale | RB | Hou | 30 | Week 14 | ||
| Josh Jacobs | RB | GB | 26 | No More Bye | ||
| Rome Odunze | WR | Chi | 22 | No More Bye | ||
| Devaughn Vele | WR | Den | 26 | Week 14 | ||
| Nico Collins | WR | Hou | 25 | Week 14 | Questionable | Hamstring |
| Darius Slayton | WR | NYG | 27 | Week 11 | Questionable | Concussion |
| Kristian Wilkerson | WR | LV | N/A | No More Bye | ||
| Ja'Marr Chase | WR | Cin | 24 | Week 12 | ||
| Quentin Johnston | WR | LAC | 23 | No More Bye | ||
| Foster Moreau | TE | NO | 27 | Week 12 | ||
| Will Dissly | TE | LAC | 28 | No More Bye | ||
| Dallas Goedert | TE | Phi | 29 | No More Bye | Questionable | Ankle |
| Mark Andrews | TE | Bal | 28 | Week 14 | ||
| Younghoe Koo | PK | Atl | 30 | Week 12 | ||
| Dustin Hopkins | PK | Cle | 34 | No More Bye | ||
| Chris Jones | DL | KC | 30 | No More Bye | ||
| T.J. Watt | DL | Pit | 30 | No More Bye | ||
| Quinnen Williams | DL | NYJ | 26 | Week 12 | ||
| Micah Parsons | DL | Dal | 26 | No More Bye | ||
| Devin Lloyd | LB | Jac | 26 | Week 12 | ||
| Christian Rozeboom | LB | LAR | N/A | No More Bye | ||
| Josey Jewell | LB | Car | 29 | Week 11 | ||
| Fred Warner | LB | SF | 27 | No More Bye | ||
| Trevon Diggs | CB | Dal | 26 | No More Bye | ||
| Shemar Jean-Charles | CB | NO | N/A | Week 12 | ||
| Kyle Hamilton | S | Bal | 23 | Week 14 | Questionable | Ankle |
| Kerby Joseph | S | Det | 24 | No More Bye |