| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Bo Nix | QB | Den | 24 | Week 14 | ||
| Patrick Mahomes | QB | KC | 29 | No More Bye | ||
| Justin Fields | QB | Pit | 25 | No More Bye | ||
| Rachaad White | RB | TB | 25 | Week 11 | ||
| Nick Chubb | RB | Cle | 28 | No More Bye | ||
| Derrick Henry | RB | Bal | 30 | Week 14 | ||
| David Montgomery | RB | Det | 27 | No More Bye | ||
| Alexander Mattison | RB | LV | 26 | No More Bye | ||
| Tim Patrick | WR | Det | 30 | No More Bye | ||
| Brandin Cooks | WR | Dal | 31 | No More Bye | NFI | Knee |
| Khalil Shakir | WR | Buf | 24 | Week 12 | ||
| Zay Flowers | WR | Bal | 24 | Week 14 | ||
| Cedric Tillman | WR | Cle | 24 | No More Bye | ||
| Darnell Mooney | WR | Atl | 27 | Week 12 | ||
| Jauan Jennings | WR | SF | N/A | No More Bye | ||
| Tre Tucker | WR | LV | N/A | No More Bye | ||
| Puka Nacua | WR | LAR | 23 | No More Bye | ||
| Evan Engram | TE | Jac | 30 | Week 12 | ||
| Zach Ertz | TE | Was | 34 | Week 14 | ||
| Harrison Butker | PK | KC | 29 | No More Bye | ||
| Maxx Crosby | DL | LV | 27 | No More Bye | ||
| Khalil Mack | DL | LAC | 33 | No More Bye | ||
| Demarcus Lawrence | DL | Dal | 32 | No More Bye | NFI | Foot |
| Nnamdi Madubuike | DL | Bal | 26 | Week 14 | ||
| Kobie Turner | DL | LAR | N/A | No More Bye | ||
| Derrick Brown | DL | Car | 26 | Week 11 | NFI | Knee - Meniscus |
| Patrick Queen | LB | Pit | 25 | No More Bye | ||
| Robert Spillane | LB | LV | 28 | No More Bye | ||
| Jahlani Tavai | LB | NE | 28 | Week 14 | ||
| C.J. Mosley | LB | NYJ | 32 | Week 12 | Questionable | Neck |
| Kaden Elliss | LB | Atl | 29 | Week 12 | ||
| Kenny Moore | CB | Ind | 29 | Week 14 | ||
| Budda Baker | S | Ari | 28 | Week 11 |