| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| RJ Harvey | RB | Den | 24 | Week 12 | ||
| Drake Maye | QB | NE | 23 | Week 14 | ||
| Jordan Love | QB | GB | 26 | Week 5 | ||
| Travis Etienne | RB | Jac | 26 | Week 8 | ||
| Isaac Guerendo | RB | SF | 25 | Week 14 | ||
| Tank Bigsby | RB | Phi | 24 | Week 9 | ||
| Kenneth Walker | RB | Sea | 24 | Week 8 | ||
| Brian Robinson | RB | SF | 26 | Week 14 | ||
| Kendre Miller | RB | NO | 23 | Week 11 | ||
| Romeo Doubs | WR | GB | 25 | Week 5 | ||
| CeeDee Lamb | WR | Dal | 26 | Week 10 | ||
| Stefon Diggs | WR | NE | 31 | Week 14 | ||
| Marvin Harrison Jr. | WR | Ari | 23 | Week 8 | ||
| Drake London | WR | Atl | 25 | Week 5 | ||
| D.J. Moore | WR | Chi | 28 | Week 5 | ||
| T.J. Hockenson | TE | Min | 28 | Week 6 | ||
| Dalton Kincaid | TE | Buf | 26 | Week 7 | ||
| Chris Boswell | PK | Pit | 34 | Week 5 | ||
| Laiatu Latu | DL | Ind | 24 | Week 11 | Questionable | Hamstring |
| Josh Sweat | DL | Ari | 28 | Week 8 | ||
| Travon Walker | DL | Jac | 24 | Week 8 | ||
| Tuli Tuipulotu | DL | LAC | 23 | Week 12 | ||
| YaYa Diaby | DL | TB | 26 | Week 9 | ||
| Nate Landman | LB | LAR | 26 | Week 8 | ||
| Jack Campbell | LB | Det | 25 | Week 8 | ||
| SirVocea Dennis | LB | TB | N/A | Week 9 | ||
| Quay Walker | LB | GB | 25 | Week 5 | ||
| Devin White | LB | LV | 27 | Week 8 | ||
| Tyrel Dodson | LB | Mia | 27 | Week 12 | ||
| Eric Murray | CB | Jac | 31 | Week 8 | ||
| Coby Bryant | CB | Sea | N/A | Week 8 | ||
| Jordan Battle | S | Cin | N/A | Week 10 | ||
| Tyler Nubin | S | NYG | 24 | Week 14 |