| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Justin Herbert | QB | LAC | 26 | **** | ||
| Gardner Minshew | QB | LV | 27 | **** | ||
| Antonio Gibson | RB | NE | 25 | **** | ||
| Travis Etienne | RB | Jac | 25 | **** | ||
| Rachaad White | RB | TB | 25 | **** | ||
| Devin Singletary | RB | NYG | 26 | **** | ||
| Austin Ekeler | RB | Was | 28 | **** | ||
| Cooper Kupp | WR | LAR | 30 | **** | ||
| Justin Jefferson | WR | Min | 25 | **** | ||
| Brandon Aiyuk | WR | SF | 26 | **** | ||
| Brandin Cooks | WR | Dal | 30 | **** | ||
| Davante Adams | WR | LV | 31 | **** | ||
| Rashee Rice | WR | KC | 24 | **** | ||
| Drake London | WR | Atl | 23 | **** | ||
| K.J. Osborn | WR | NE | 26 | **** | ||
| Donald Parham | TE | LAC | 26 | **** | ||
| Evan Engram | TE | Jac | 29 | **** | ||
| George Kittle | TE | SF | 30 | **** | ||
| Jake Moody | PK | SF | 24 | **** | ||
| Blake Grupe | PK | NO | 25 | **** | ||
| Quinnen Williams | DL | NYJ | 26 | **** | ||
| Rashan Gary | DL | GB | 26 | **** | ||
| Jonathan Allen | DL | Was | 29 | **** | ||
| Aaron Donald | DL | F/A | 32 | **** | ||
| Lavonte David | LB | TB | 34 | **** | ||
| Denzel Perryman | LB | LAC | 31 | **** | ||
| De'Vondre Campbell | LB | GB | 30 | **** | ||
| Patrick Queen | LB | Pit | 24 | **** | ||
| Quay Walker | LB | GB | 23 | **** | ||
| Tyson Campbell | CB | Jac | 24 | **** | ||
| Deommodore Lenoir | CB | SF | 24 | **** | ||
| Rudy Ford | CB | GB | N/A | **** | ||
| Antoine Winfield | S | TB | 25 | **** |