| Position | Starters | Proteam | TW | PPG | Total | Breakdown |
|---|---|---|---|---|---|---|
| QB | Patrick Mahomes | KC | 24.32 | 24.59 | 319.68 | 258 Pass, 20 Rush, 2 TD |
| RB | David Montgomery | Chi | 11.1 | 13.01 | 117.10 | 42 Rush, 39 Receiving, 6 Rec |
| RB | Wendell Smallwood | Was | 0.0 | 1.75 | 3.50 | Played, No Stats |
| WR | Tee Higgins | Cin | 13.9 | 12.25 | 134.70 | 114 Receiving, 5 Rec |
| WR | Tyler Lockett | Sea | 24.7 | 12.72 | 165.30 | 142 Receiving, 5 Rec, 1 TD, 1 2-Pt |
| WR | Hunter Renfrow | LV | 23.2 | 12.34 | 160.40 | 117 Receiving, 13 Rec, 1 TD, 1 Fumb |
| TE | Rob Gronkowski | TB | 8.7 | 13.10 | 104.80 | 62 Receiving, 5 Rec |
| HB (TE) | Zach Ertz | Ari | 6.7 | 8.10 | 105.30 | 42 Receiving, 5 Rec |
| PK | Justin Tucker | Bal | 15.0 | 10.08 | 131.00 | 1 FG(40-49), 2 FG(50-59), 1 XP |
| DL | Arik Armstead | SF | 4.0 | 4.00 | 52.00 | 3 Tackles, 1 Assist |
| DL | Dante Fowler | Atl | 7.0 | 5.50 | 55.00 | 3 Tackles, 1.0 Sack |
| DL | Sam Hubbard | Cin | 2.0 | 7.08 | 92.00 | 2 Assists |
| LB | Markus Golden | Ari | 0.0 | 7.23 | 94.00 | Played, No Stats |
| LB | Shaq Thompson | Car | 11.0 | 10.30 | 103.00 | 9 Tackles, 2 Assists |
| LB | Fred Warner | SF | 7.0 | 9.00 | 108.00 | 1 Tackle, 6 Assists |
| CB | Donte Jackson | Car | DNP | 6.83 | 82.00 | Did Not Play |
| S | Jordan Poyer | Buf | 11.0 | 9.67 | 116.00 | 7 Tackles, 3 Assists, 1 PD |
| Position | 1st Backups | Proteam | TW | PPG | Total | Breakdown |
| QB | Taylor Heinicke | Was | 0(10.68) | 18.71 | 243.24 | 122 Pass, 8 Rush, 1 TD, 1 Int, 1 2-Pt, 1 Fumb |
| RB | Michael Carter | NYJ | DNP | 11.28 | 112.80 | Did Not Play |
| WR | Chase Claypool | Pit | 0(13.5) | 10.04 | 110.40 | 2 Rush, 93 Receiving, 8 Rec |
| TE | C.J. Uzomah | Cin | 0(7.6) | 6.86 | 89.20 | 56 Receiving, 4 Rec |
| HB (TE) | T.J. Hockenson | Det | DNP | 9.57 | 114.80 | Did Not Play |
| DL | Derrick Brown | Car | 0(4.0) | 3.62 | 47.00 | 4 Tackles |
| LB | Joe Schobert | Pit | 0(7.0) | 7.69 | 100.00 | 4 Tackles, 3 Assists |
| Position | 2nd Backups | Proteam | TW | PPG | Total | Breakdown |
| WR | Robby Anderson | Car | 0(17.9) | 6.12 | 79.50 | 84 Receiving, 7 Rec, 1 TD |
| HB (WR) | Tim Patrick | Den | 0(3.1) | 7.92 | 102.90 | 21 Receiving, 2 Rec |
| Offense = 127.62 Defense = 42 Total = 169.62 | ||||||
| Position | Bench | Proteam | TW | PPG | Total | Breakdown |
| HB (RB) | David Johnson | Hou | DNP | 5.27 | 58.00 | Did Not Play |
| HB (WR) | Kendrick Bourne | NE | DNP | 9.80 | 127.40 | Team had a Bye |
| HB (WR) | DJ Chark | Jac | DNP | 7.72 | 30.90 | Did Not Play |
| HB (WR) | T.Y. Hilton | Ind | DNP | 5.20 | 31.20 | Team had a Bye |
| HB (WR) | JuJu Smith-Schuster | Pit | DNP | 5.46 | 27.30 | Did Not Play |
| HB (LB) | Jerome Baker | Mia | DNP | 6.83 | 82.00 | Team had a Bye |
| HB (RB) | Godwin Igwebuike | Det | 0(1.5) | 1.04 | 13.50 | 25 Rush, 1 Fumb |
| Position | Injured Reserve | Proteam | TW | PPG | Total | Breakdown |
| HB (RB) | Cam Akers | LAR | DNP | 0.00 | 0 | Did Not Play |