| Position | Starters | Proteam | TW | PPG | Total | Breakdown |
|---|---|---|---|---|---|---|
| QB | Justin Herbert | LAC | 18.94 | 26.84 | 402.66 | 336 Pass, 15 Rush, 1 TD, 2 Int, 1 2-Pt |
| RB | Dontrell Hilliard | Ten | 2.4 | 7.10 | 42.60 | 20 Rush, - 6 Receiving, 2 Rec |
| RB | Jonathan Taylor | Ind | 10.8 | 21.75 | 326.20 | 108 Rush |
| WR | Marquise Brown | Bal | 6.9 | 12.45 | 174.30 | 44 Receiving, 5 Rec |
| WR | Nico Collins | Hou | 10.8 | 4.53 | 54.40 | 33 Receiving, 3 Rec, 1 TD |
| WR | Amon-Ra St. Brown | Det | 21.5 | 8.59 | 128.80 | 19 Rush, 91 Receiving, 9 Rec, 1 TD |
| TE | Tyler Higbee | LAR | 6.6 | 6.15 | 86.10 | 41 Receiving, 5 Rec |
| HB (WR) | Darnell Mooney | Chi | 8.4 | 9.61 | 144.20 | 2 Rush, 57 Receiving, 5 Rec |
| PK | Daniel Carlson | LV | 6.0 | 9.07 | 136.00 | 1 FG(40-49), 2 XP |
| DL | Chris Jones | KC | 3.0 | 5.08 | 61.00 | 2 Tackles, 1 Assist |
| DL | Josh Sweat | Phi | 12.0 | 4.60 | 69.00 | 2 Tackles, 2 Assists, 1.0 Sack, 1 FF, 1 PD |
| DL | Darrell Taylor | Sea | 3.0 | 4.36 | 61.00 | 2 Tackles, 1 Assist |
| LB | De'Vondre Campbell | GB | 14.0 | 11.13 | 167.00 | 12 Tackles, 1 Assist, 1 PD |
| LB | Tae Crowder | NYG | 4.0 | 8.33 | 125.00 | 1 Tackle, 3 Assists |
| LB | Bobby Wagner | Sea | 12.0 | 12.53 | 188.00 | 4 Tackles, 8 Assists |
| CB | Bobby McCain | Was | 10.0 | 5.00 | 75.00 | 7 Tackles, 3 Assists |
| S | Derwin James | LAC | DNP | 10.31 | 134.00 | Did Not Play |
| Position | 1st Backups | Proteam | TW | PPG | Total | Breakdown |
| RB | Ameer Abdullah | Car | 0(2.4) | 3.61 | 50.60 | 1 Rush, 8 Receiving, 3 Rec |
| WR | Rashod Bateman | Bal | 0(10.6) | 6.80 | 68.00 | 26 Receiving, 4 Rec, 1 TD |
| TE | Gerald Everett | Sea | 0(14.8) | 6.78 | 88.20 | 68 Receiving, 4 Rec, 1 TD |
| HB (RB) | Kenneth Gainwell | Phi | 0(1.1) | 6.49 | 90.80 | 6 Receiving, 1 Rec |
| DL | Quinnen Williams | NYJ | DNP | 5.29 | 74.00 | Did Not Play |
| LB | Anthony Walker | Cle | 0(9.0) | 9.27 | 102.00 | 3 Tackles, 6 Assists |
| S | Landon Collins | Was | DNP | 8.54 | 111.00 | Did Not Play |
| Position | 2nd Backups | Proteam | TW | PPG | Total | Breakdown |
| QB | Jordan Love | GB | DNP | 3.80 | 15.22 | Did Not Play |
| RB | Zack Moss | Buf | 0(3.0) | 8.04 | 88.40 | 12 Rush, 13 Receiving, 1 Rec |
| Offense = 92.34 Defense = 58 Total = 150.34 | ||||||
| Position | Bench | Proteam | TW | PPG | Total | Breakdown |
| TE | Irv Smith | Min | DNP | 0.00 | 0 | Did Not Play |
| QB | Trey Lance | SF | DNP | 10.37 | 51.86 | Did Not Play |
| RB | Kenyan Drake | LV | DNP | 7.29 | 87.50 | Did Not Play |
| RB | Gus Edwards | Bal | DNP | 0.00 | 0 | Did Not Play |
| RB | Leonard Fournette | TB | DNP | 15.79 | 221.00 | Did Not Play |
| WR | Corey Davis | NYJ | DNP | 9.91 | 89.20 | Did Not Play |
| DL | Danielle Hunter | Min | DNP | 8.86 | 62.00 | Did Not Play |
| Position | Injured Reserve | Proteam | TW | PPG | Total | Breakdown |
| RB | Travis Etienne | Jac | DNP | 0.00 | 0 | Did Not Play |