| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | Dak Prescott | Dal | 30.04 | 23.92 | 358.76 | 226 Pass, 20 Rush, 3 TD, 1 2-Pt, 1 Fumb |
| RB | Damien Harris | NE | 17.20 | 13.41 | 187.80 | 35 Rush, 12 Receiving, 1 Rec, 2 TD |
| RB | Najee Harris | Pit | 28.10 | 16.01 | 256.20 | 188 Rush, 18 Receiving, 3 Rec, 1 TD |
| WR | Antonio Brown | TB | 4.10 | 12.51 | 100.10 | 26 Receiving, 3 Rec |
| WR | Cooper Kupp | LAR | 18.50 | 21.49 | 343.90 | 95 Receiving, 6 Rec, 1 TD |
| WR | Mike Williams | LAC | 13.80 | 12.41 | 186.20 | 63 Receiving, 3 Rec, 1 TD |
| TE | Kyle Pitts | Atl | 7.90 | 8.80 | 140.80 | 69 Receiving, 2 Rec |
| HB | Brandin Cooks | Hou | 16.10 | 12.18 | 182.70 | 66 Receiving, 7 Rec, 1 TD |
| PK | Daniel Carlson | LV | 13.00 | 9.31 | 149.00 | 1 FG(<40), 2 FG(40-49), 2 XP |
| DL | Marcus Davenport | NO | 5.00 | 7.60 | 76.00 | 2 Assists, 1 Fum Rcvy |
| DL | Chris Jones | KC | 12.00 | 5.62 | 73.00 | 4 Tackles, 2.0 Sacks |
| DL | Josh Sweat | Phi | 13.00 | 5.13 | 82.00 | 3 Tackles, 2 Assists, 1.5 Sacks, 2 PD |
| LB | Tae Crowder | NYG | 12.00 | 8.56 | 137.00 | 3 Tackles, 3 Assists, 1 Int, 1 PD |
| LB | Kyzir White | LAC | 11.00 | 9.75 | 156.00 | 5 Tackles, 6 Assists |
| LB | Quincy Williams | NYJ | 7.00 | 6.63 | 106.00 | 2 Tackles, 5 Assists |
| CB | Jalen Ramsey | LAR | 3.00 | 7.27 | 109.00 | 2 Tackles, 1 PD |
| S | Derwin James | LAC | 6.00 | 10.00 | 140.00 | 4 Tackles, 2 Assists |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Andy Dalton | Chi | 0(12.32) | 10.44 | 83.50 | 173 Pass, 14 Rush, 1 TD, 1 Int |
| RB | Phillip Lindsay | Mia | 0(1.40) | 3.03 | 39.40 | 1 Rush, 8 Receiving, 1 Rec |
| WR | Amon-Ra St. Brown | Det | 0(31.40) | 10.01 | 160.20 | 23 Rush, 111 Receiving, 8 Rec, 2 TD, 1 2-Pt |
| TE | Jared Cook | LAC | DNP | 6.56 | 98.40 | Did Not Play |
| WR | Nico Collins | Hou | 0(4.50) | 4.53 | 58.90 | 35 Receiving, 2 Rec |
| PK | Younghoe Koo | Atl | 0(7.00) | 7.13 | 114.00 | 2 FG(<40), 1 XP |
| DL | Javon Hargrave | Phi | 0(5.00) | 6.13 | 98.00 | 2 Tackles, 3 Assists |
| LB | Devin Bush | Pit | DNP | 6.31 | 82.00 | Did Not Play |
| S | Jordan Fuller | LAR | 0(12.00) | 7.31 | 117.00 | 4 Tackles, 2 Assists, 1 Int, 1 PD |
| Pos. | 2nd Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Justin Fields | Chi | DNP | 12.15 | 145.80 | Did Not Play |
| WR | Tyler Boyd | Cin | 0(11.60) | 9.40 | 150.34 | 36 Receiving, 4 Rec, 1 TD |
| WR | Rashod Bateman | Bal | 0(9.30) | 7.03 | 77.30 | 58 Receiving, 7 Rec |
| Offense = 148.74 Defense = 69 Total = 217.74 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| RB | J.K. Dobbins | Bal | DNP | 0.00 | 0.00 | Did Not Play |
| RB | Miles Sanders | Phi | DNP | 8.77 | 105.20 | Did Not Play |
| WR | DJ Chark | Jac | DNP | 7.72 | 30.90 | Did Not Play |
| WR | Bryan Edwards | LV | 0.00 | 5.59 | 83.80 | Played, No Stats |