| Position | Starters | Proteam | TW | PPG | Total | Breakdown |
|---|---|---|---|---|---|---|
| QB | Joe Burrow | Cin | 42.84 | 24.01 | 384.24 | 446 Pass, 10 Rush, 4 TD |
| RB | Aaron Jones | GB | 13.1 | 13.60 | 204.00 | 76 Rush, 30 Receiving, 5 Rec |
| RB | Jonathan Taylor | Ind | 17.9 | 21.51 | 344.10 | 108 Rush, 6 Receiving, 1 Rec, 1 TD |
| WR | Diontae Johnson | Pit | 13.1 | 14.29 | 214.30 | 31 Receiving, 8 Rec, 1 TD |
| WR | CeeDee Lamb | Dal | 6.6 | 12.52 | 187.80 | 51 Receiving, 3 Rec |
| WR | D.K. Metcalf | Sea | 27.9 | 12.41 | 198.50 | 6 Rush, 63 Receiving, 6 Rec, 3 TD |
| TE | Dallas Goedert | Phi | 10.1 | 9.13 | 137.00 | 71 Receiving, 6 Rec |
| HB (RB) | Najee Harris | Pit | 28.1 | 16.01 | 256.20 | 188 Rush, 18 Receiving, 3 Rec, 1 TD |
| PK | Greg Zuerlein | Dal | 2.0 | 8.27 | 124.00 | 2 XP |
| DL | Marcus Davenport | NO | 5.0 | 7.60 | 76.00 | 2 Assists, 1 Fum Rcvy |
| DL | Rasheem Green | Sea | 3.0 | 4.63 | 74.00 | 1 Tackle, 2 Assists |
| DL | Randy Gregory | Dal | 5.0 | 5.36 | 59.00 | 3 Tackles, 2 Assists |
| LB | Eric Kendricks | Min | 9.0 | 11.87 | 178.00 | 6 Tackles, 3 Assists |
| LB | Patrick Queen | Bal | 1.0 | 6.69 | 107.00 | 1 Tackle |
| LB | Shaq Thompson | Car | 7.0 | 9.31 | 121.00 | 4 Tackles, 3 Assists |
| CB | Tavierre Thomas | Hou | 2.0 | 6.31 | 101.00 | 1 Tackle, 1 Assist |
| S | Jessie Bates | Cin | 5.0 | 6.53 | 98.00 | 2 Tackles, 2 Assists, 1 PD |
| Position | 1st Backups | Proteam | TW | PPG | Total | Breakdown |
| QB | Davis Mills | Hou | 0(10.92) | 13.06 | 156.72 | 163 Pass, 4 Rush, 1 TD, 1 Int |
| RB | Sony Michel | LAR | 0(17.4) | 8.21 | 131.40 | 74 Rush, 25 Receiving, 3 Rec, 1 TD |
| WR | Amon-Ra St. Brown | Det | 0(31.4) | 10.01 | 160.20 | 23 Rush, 111 Receiving, 8 Rec, 2 TD, 1 2-Pt |
| TE | Brevin Jordan | Hou | 0(1.4) | 5.72 | 45.80 | 9 Receiving, 1 Rec |
| HB (RB) | Tony Pollard | Dal | 0(7.3) | 9.54 | 143.10 | 9 Rush, 49 Receiving, 3 Rec |
| PK | Jake Elliott | Phi | 0(10.0) | 8.81 | 141.00 | 2 FG(40-49), 2 XP |
| DL | Jeffery Simmons | Ten | 0(1.0) | 5.56 | 89.00 | 1 Tackle |
| LB | Germaine Pratt | Cin | DNP | 7.53 | 113.00 | Did Not Play |
| CB | Jalen Ramsey | LAR | 0(3.0) | 7.27 | 109.00 | 2 Tackles, 1 PD |
| S | Jordan Fuller | LAR | 0(12.0) | 7.31 | 117.00 | 4 Tackles, 2 Assists, 1 Int, 1 PD |
| Position | 2nd Backups | Proteam | TW | PPG | Total | Breakdown |
| RB | Duke Johnson | Mia | 0(7.5) | 2.56 | 38.40 | 49 Rush, 16 Receiving, 2 Rec |
| HB (WR) | Van Jefferson | LAR | 0(8.3) | 8.69 | 139.10 | 63 Receiving, 4 Rec |
| DL | Dante Fowler | Atl | 0(3.0) | 4.77 | 62.00 | 2 Tackles, 1 Assist |
| LB | Isaiah Simmons | Ari | 0(13.0) | 8.06 | 129.00 | 8 Tackles, 2 Assists, 1 FF |
| Offense = 161.64 Defense = 37 Total = 198.64 | ||||||
| Position | Bench | Proteam | TW | PPG | Total | Breakdown |
| RB | Chris Evans | Cin | 0(0.0) | 2.18 | 28.40 | Played, No Stats |
| WR | Robert Woods | LAR | DNP | 12.78 | 115.00 | Did Not Play |
| Position | Injured Reserve | Proteam | TW | PPG | Total | Breakdown |
| DL | Chase Young | Was | DNP | 4.67 | 42.00 | Did Not Play |