| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | Geno Smith | Sea | 24.36 | 16.85 | 269.64 | 189 Pass, 28 Rush, 2 TD, 1 2-Pt |
| RB | Breece Hall | NYJ | 28.00 | 14.85 | 252.50 | 178 Rush, 12 Receiving, 2 Rec, 1 TD, 1 2-Pt |
| RB | David Montgomery | Det | 10.00 | 14.30 | 200.20 | 40 Rush, 1 TD |
| WR | Jayden Reed | GB | 13.20 | 11.57 | 185.20 | 112 Receiving, 4 Rec |
| WR | Jaxon Smith-Njigba | Sea | 2.90 | 6.96 | 118.30 | 14 Receiving, 3 Rec |
| WR | Adam Thielen | Car | 2.20 | 10.56 | 179.50 | 12 Receiving, 2 Rec |
| TE | Dallas Goedert | Phi | 0.90 | 7.63 | 106.80 | 4 Receiving, 1 Rec |
| HB | Kenneth Gainwell | Phi | 6.20 | 5.21 | 83.38 | 62 Rush |
| PK | Brandon Aubrey | Dal | 9.00 | 10.47 | 178.00 | 1 FG(50-59), 5 XP, 1 Miss(<40) |
| DL | Maxx Crosby | LV | 6.00 | 9.35 | 159.00 | 2 Tackles, 1.0 Sack |
| DL | Danielle Hunter | Min | 10.00 | 9.59 | 163.00 | 5 Tackles, 1 Assist, 1.0 Sack |
| DL | Andrew Van Ginkel | Mia | 1.00 | 6.76 | 115.00 | 1 Tackle |
| LB | Samson Ebukam | Ind | 3.00 | 6.12 | 104.00 | 1 Tackle, 2 Assists |
| LB | Dre Greenlaw | SF | 0.00 | 8.19 | 131.00 | Played, No Stats |
| LB | C.J. Mosley | NYJ | 7.00 | 10.24 | 174.00 | 3 Tackles, 4 Assists |
| CB | Rasul Douglas | Buf | 0.00 | 7.44 | 119.00 | Played, No Stats |
| S | Jevon Holland | Mia | 1.00 | 8.25 | 99.00 | 1 Assist |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Nick Mullens | Min | 0(24.64) | 13.46 | 80.74 | 396 Pass, 8 Rush, 2 TD, 2 Int |
| WR | Justin Watson | KC | 0 | 4.50 | 76.50 | Played, No Stats |
| TE | Travis Kelce | KC | DNP | 11.59 | 173.90 | Did Not Play |
| DL | Boye Mafe | Sea | 0(3.00) | 6.31 | 101.00 | 1 Tackle, 2 Assists |
| LB | Shaquille Leonard | Phi | 0(5.00) | 6.57 | 92.00 | 3 Tackles, 2 Assists |
| CB | Alontae Taylor | NO | 0(7.00) | 6.29 | 107.00 | 1 Tackle, 1 Int, 1 PD |
| S | Dax Hill | Cin | 0(5.00) | 7.94 | 135.00 | 4 Tackles, 1 Assist |
| Pos. | 2nd Backup | Proteam | TW | PPG | Total | Breakdown |
| DL | Chris Jones | KC | 0(5.00) | 4.75 | 76.00 | 1 Tackle, 1.0 Sack |
| LB | Jack Campbell | Det | 0(16.00) | 6.12 | 104.00 | 7 Tackles, 5 Assists, 1.0 Sack |
| Offense = 96.76 Defense = 28 Total = 124.76 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| QB | Kirk Cousins | Min | DNP | 23.72 | 189.74 | Did Not Play |
| QB | Kenny Pickett | Pit | 0.00 | 9.40 | 122.20 | Played, No Stats |
| RB | Dalvin Cook | NYJ | DNP | 2.17 | 34.70 | Did Not Play |
| RB | Kyren Williams | LAR | DNP | 20.08 | 241.00 | Did Not Play |
| WR | Keenan Allen | LAC | DNP | 17.51 | 227.66 | Did Not Play |
| WR | Tee Higgins | Cin | DNP | 9.72 | 116.60 | Did Not Play |
| DL | George Karlaftis | KC | 0.00 | 5.59 | 95.00 | Played, No Stats |
| Pos. | Injured List | Proteam | TW | PPG | Total | Breakdown |
| RB | J.K. Dobbins | Bal | DNP | 0.00 | 0.00 | Did Not Play |