| Position | Starters | Proteam | TW | PPG | Total | Breakdown |
|---|---|---|---|---|---|---|
| QB | Kyler Murray | Ari | 26.92 | 25.34 | 329.38 | 263 Pass, 44 Rush, 2 TD |
| RB | Joe Mixon | Cin | 12.1 | 16.74 | 267.90 | 46 Rush, 40 Receiving, 7 Rec |
| RB | D'Andre Swift | Det | 4.9 | 13.86 | 166.30 | 32 Rush, 7 Receiving, 2 Rec |
| WR | Stefon Diggs | Buf | 7.5 | 13.45 | 215.20 | - 2 Rush, 52 Receiving, 5 Rec |
| WR | Justin Jefferson | Min | 8.8 | 16.11 | 257.80 | 58 Receiving, 6 Rec |
| WR | Cooper Kupp | LAR | 18.5 | 21.49 | 343.90 | 95 Receiving, 6 Rec, 1 TD |
| TE | Gerald Everett | Sea | 5.1 | 6.66 | 93.30 | 36 Receiving, 3 Rec |
| HB (WR) | Davante Adams | GB | 25.1 | 18.29 | 274.30 | 136 Receiving, 11 Rec, 1 TD |
| PK | Tyler Bass | Buf | 3.0 | 8.25 | 132.00 | 3 XP |
| DL | Shelby Harris | Den | 4.0 | 4.80 | 72.00 | 1 Tackle, 3 Assists |
| DL | Cameron Heyward | Pit | 10.0 | 8.69 | 139.00 | 4 Tackles, 1.0 Sack, 2 PD |
| DL | Christian Wilkins | Mia | 11.0 | 6.63 | 106.00 | 6 Tackles, 5 Assists |
| LB | Jordan Hicks | Ari | 1.0 | 9.00 | 144.00 | 1 Tackle |
| LB | Micah Parsons | Dal | 5.0 | 9.19 | 147.00 | 4 Tackles, 1 Assist |
| LB | Roquan Smith | Chi | 9.0 | 11.31 | 181.00 | 6 Tackles, 3 Assists |
| CB | JC Jackson | NE | 10.0 | 7.69 | 123.00 | 4 Tackles, 1 Int, 1 PD |
| S | Harrison Smith | Min | 8.0 | 9.64 | 135.00 | 5 Tackles, 3 Assists |
| Position | 1st Backups | Proteam | TW | PPG | Total | Breakdown |
| QB | Colt McCoy | NYG | DNP | 6.04 | 48.30 | Did Not Play |
| RB | Jamaal Williams | Det | 0(11.9) | 8.43 | 101.10 | 22 Rush, 22 Receiving, 3 Rec, 1 TD |
| WR | Michael Gallup | Dal | 0(11.1) | 8.22 | 74.00 | 36 Receiving, 3 Rec, 1 TD |
| TE | Mike Gesicki | Mia | 0(7.1) | 7.83 | 125.30 | 51 Receiving, 4 Rec |
| HB (WR) | Christian Kirk | Ari | 0(10.9) | 10.23 | 163.72 | 79 Receiving, 6 Rec |
| PK | Evan McPherson | Cin | 0(11.0) | 9.50 | 152.00 | 1 FG(<40), 1 FG(40-49), 4 XP |
| DL | Da'Ron Payne | Was | 0(3.0) | 4.75 | 76.00 | 2 Tackles, 1 Assist |
| LB | Tremaine Edmunds | Buf | 0(7.0) | 7.86 | 110.00 | 5 Tackles, 2 Assists |
| CB | Anthony Brown | Dal | 0(4.0) | 7.00 | 112.00 | 2 Tackles, 2 PD |
| S | Jayron Kearse | Dal | 0(7.0) | 8.13 | 130.00 | 5 Tackles, 1 Assist, 1 PD |
| Position | 2nd Backups | Proteam | TW | PPG | Total | Breakdown |
| RB | Samaje Perine | Cin | 0(1.9) | 4.65 | 69.70 | 4 Rush, 10 Receiving, 1 Rec |
| WR | Isaiah McKenzie | Buf | 0(1.4) | 2.94 | 41.10 | 3 Rush, 6 Receiving, 1 Rec |
| TE | C.J. Uzomah | Cin | 0(5.2) | 6.49 | 103.80 | 32 Receiving, 4 Rec |
| HB (WR) | A.J. Green | Ari | 0(8.9) | 8.37 | 125.50 | 74 Receiving, 3 Rec |
| Offense = 111.92 Defense = 58 Total = 169.92 | ||||||
| Position | Bench | Proteam | TW | PPG | Total | Breakdown |
| HB (RB) | Mark Ingram | NO | DNP | 6.86 | 96.10 | Did Not Play |
| HB (WR) | Antoine Wesley | Ari | 0(17.0) | 2.85 | 45.60 | 30 Receiving, 4 Rec, 2 TD |