| Position | Starters | Proteam | TW | PPG | Total | Breakdown |
|---|---|---|---|---|---|---|
| QB | Tua Tagovailoa | Mia | 12.4 | 21.69 | 281.92 | 310 Pass, 1 TD, 3 Int |
| RB | Derrick Henry | Ten | 18.6 | 18.53 | 277.96 | 126 Rush, 2 Rec, 1 TD, 1 Fumb |
| RB | Raheem Mostert | Mia | 4.9 | 9.11 | 127.60 | 45 Rush, 4 Receiving, 2 Rec, 1 Fumb |
| WR | Stefon Diggs | Buf | 3.6 | 16.18 | 242.70 | 26 Receiving, 2 Rec |
| WR | Russell Gage | TB | 9.0 | 7.75 | 85.30 | 65 Receiving, 5 Rec |
| WR | Jaylen Waddle | Mia | 22.8 | 13.88 | 208.20 | 143 Receiving, 5 Rec, 1 TD |
| TE | Taysom Hill | NO | 11.6 | 9.23 | 129.24 | 56 Rush, 1 TD |
| HB (RB) | Joe Mixon | Cin | 14.3 | 14.94 | 194.20 | 65 Rush, 43 Receiving, 7 Rec |
| PK | Evan McPherson | Cin | 3.0 | 7.80 | 117.00 | 1 FG(<40), 1 XP, 1 Miss(<40) |
| DL | Denico Autry | Ten | 16.0 | 6.18 | 68.00 | 5 Tackles, 2 Assists, 1.0 Sack, 1 FF, 2 PD |
| DL | DeForest Buckner | Ind | 14.0 | 7.33 | 110.00 | 2 Tackles, 3 Assists, 1.5 Sacks, 1 FF |
| DL | Frank Clark | KC | 2.0 | 4.85 | 63.00 | 2 Tackles |
| LB | Jordan Hicks | Min | 11.0 | 10.20 | 153.00 | 5 Tackles, 5 Assists, 1 PD |
| LB | Micah Parsons | Dal | 3.0 | 8.87 | 133.00 | 2 Tackles, 1 Assist |
| LB | Roquan Smith | Bal | 15.0 | 12.27 | 184.00 | 7 Tackles, 8 Assists |
| CB | Nate Hobbs | LV | 6.0 | 8.33 | 75.00 | 5 Tackles, 1 Assist |
| S | Jalen Pitre | Hou | 15.0 | 10.73 | 161.00 | 7 Tackles, 2 Assists, 1 Int, 1 PD |
| Position | 1st Backups | Proteam | TW | PPG | Total | Breakdown |
| QB | Geno Smith | Sea | 0(14.2) | 22.08 | 331.14 | 215 Pass, 16 Rush, 1 TD, 1 Int |
| RB | D'Andre Swift | Det | 0(3.0) | 10.77 | 129.30 | 12 Rush, 13 Receiving, 1 Rec |
| WR | Chris Moore | Hou | 0(3.5) | 6.04 | 84.50 | 25 Receiving, 2 Rec |
| TE | Gerald Everett | LAC | 0(0.0) | 6.66 | 93.20 | Played, No Stats |
| HB (RB) | Samaje Perine | Cin | 0(3.7) | 8.03 | 120.40 | 3 Rush, 19 Receiving, 3 Rec |
| PK | Younghoe Koo | Atl | 0(9.0) | 8.47 | 127.00 | 3 FG(<40) |
| DL | Leonard Williams | NYG | 0(8.0) | 5.64 | 62.00 | 2 Tackles, 2 Assists, 1.0 Sack |
| LB | Alex Singleton | Den | 0(20.0) | 9.87 | 148.00 | 13 Tackles, 7 Assists |
| CB | Denzel Ward | Cle | 0(2.0) | 7.50 | 90.00 | 1 Tackle, 1 PD |
| Position | 2nd Backups | Proteam | TW | PPG | Total | Breakdown |
| QB | Gardner Minshew | Phi | 0(27.7) | 7.22 | 28.86 | 355 Pass, 5 Rush, 3 TD, 2 Int, 1 Fumb |
| RB | Jeff Wilson | Mia | 0(10.5) | 9.43 | 132.00 | 37 Rush, 3 Receiving, 1 Rec, 1 TD |
| WR | Trent Sherfield | Mia | 0(3.5) | 4.31 | 64.70 | 25 Receiving, 2 Rec |
| HB (WR) | Josh Reynolds | Det | 0(4.1) | 6.82 | 81.80 | 31 Receiving, 2 Rec |
| DL | George Karlaftis | KC | 0(6.0) | 3.47 | 52.00 | 1 Tackle, 1.0 Sack, 1 PD |
| LB | Devin Lloyd | Jac | 0(15.0) | 9.00 | 135.00 | 6 Tackles, 3 Assists, 1 Int, 1 PD |
| Offense = 100.2 Defense = 82 Total = 182.2 | ||||||
| Position | Bench | Proteam | TW | PPG | Total | Breakdown |
| DL | Aaron Donald | LAR | DNP | 7.00 | 77.00 | Did Not Play |
| Position | Injured Reserve | Proteam | TW | PPG | Total | Breakdown |
| WR | Cooper Kupp | LAR | DNP | 18.32 | 164.90 | Did Not Play |