| Position | Starters | Proteam | TW | PPG | Total | Breakdown |
|---|---|---|---|---|---|---|
| QB | Matthew Stafford | LAR | 19.26 | 24.39 | 390.22 | 309 Pass, - 1 Rush, 2 TD, 2 Int, 1 Fumb |
| RB | D'Onta Foreman | Ten | 19.2 | 5.43 | 81.50 | 132 Rush, 1 TD |
| RB | Ke'Shawn Vaughn | TB | 5.5 | 2.14 | 23.50 | 31 Rush, 14 Receiving, 2 Rec |
| WR | A.J. Brown | Ten | 5.1 | 11.22 | 134.60 | 41 Receiving, 2 Rec |
| WR | Gabriel Davis | Buf | 5.5 | 6.87 | 103.00 | 40 Receiving, 3 Rec |
| WR | Diontae Johnson | Pit | 13.1 | 14.29 | 214.30 | 31 Receiving, 8 Rec, 1 TD |
| TE | Josiah Deguara | GB | 2.1 | 2.33 | 34.90 | 11 Receiving, 2 Rec |
| HB (RB) | Ezekiel Elliott | Dal | 3.5 | 13.75 | 220.06 | 16 Rush, 14 Receiving, 1 Rec |
| PK | Justin Tucker | Bal | 15.0 | 9.69 | 155.00 | 2 FG(<40), 2 FG(40-49), 1 XP |
| DL | Carlos Dunlap | Sea | 1.0 | 4.13 | 66.00 | 1 Tackle |
| DL | Sam Hubbard | Cin | 5.0 | 6.44 | 103.00 | 2 Tackles, 3 Assists |
| DL | Cameron Jordan | NO | 22.0 | 7.47 | 112.00 | 6 Tackles, 2 Assists, 3.5 Sacks |
| LB | Eric Kendricks | Min | 9.0 | 11.87 | 178.00 | 6 Tackles, 3 Assists |
| LB | Roquan Smith | Chi | 9.0 | 11.31 | 181.00 | 6 Tackles, 3 Assists |
| LB | T.J. Watt | Pit | 23.0 | 12.29 | 172.00 | 5 Tackles, 4.0 Sacks, 2 PD |
| CB | M.J. Stewart | Cle | 8.0 | 3.25 | 52.00 | 4 Tackles, 2 Assists, 2 PD |
| S | Kevin Byard | Ten | 4.0 | 9.13 | 146.00 | 3 Tackles, 1 Assist |
| Position | 1st Backups | Proteam | TW | PPG | Total | Breakdown |
| QB | Ben Roethlisberger | Pit | 0(8.82) | 16.92 | 253.74 | 123 Pass, - 1 Rush, 1 TD, 1 Int |
| RB | James Conner | Ari | DNP | 15.35 | 214.90 | Did Not Play |
| WR | Marquise Brown | Bal | 0(3.3) | 11.84 | 177.60 | 28 Receiving, 3 Rec, 1 Fumb |
| TE | Tyler Conklin | Min | 0(7.2) | 6.64 | 106.20 | 47 Receiving, 5 Rec |
| HB (WR) | Russell Gage | Atl | 0(6.5) | 8.38 | 108.90 | 50 Receiving, 3 Rec |
| PK | Randy Bullock | Ten | 0(11.0) | 7.69 | 123.00 | 1 FG(<40), 1 FG(40-49), 4 XP |
| DL | Maxx Crosby | LV | 0(2.0) | 4.81 | 77.00 | 2 Tackles |
| LB | Kwon Alexander | NO | 0(10.0) | 6.27 | 69.00 | 6 Tackles, 2 Assists, 0.5 Sack |
| CB | Xavien Howard | Mia | 0(3.0) | 6.87 | 103.00 | 2 Tackles, 1 PD |
| S | Derwin James | LAC | 0(6.0) | 10.00 | 140.00 | 4 Tackles, 2 Assists |
| Position | 2nd Backups | Proteam | TW | PPG | Total | Breakdown |
| QB | Mac Jones | NE | 0(28.28) | 16.13 | 258.14 | 227 Pass, 12 Rush, 3 TD |
| WR | Laquon Treadwell | Jac | 0(11.7) | 3.50 | 56.00 | 87 Receiving, 6 Rec |
| Offense = 88.26 Defense = 81 Total = 169.26 | ||||||
| Position | Bench | Proteam | TW | PPG | Total | Breakdown |
| RB | Leonard Fournette | TB | DNP | 15.79 | 221.00 | Did Not Play |
| WR | Josh Reynolds | Det | 0(0.0) | 5.38 | 64.50 | Played, No Stats |
| WR | Golden Tate | Ten | 0(0.0) | 0.00 | 0.00 | Played, No Stats |
| TE | T.J. Hockenson | Det | DNP | 9.57 | 114.80 | Did Not Play |
| Position | Injured Reserve | Proteam | TW | PPG | Total | Breakdown |
| RB | Christian McCaffrey | Car | DNP | 15.57 | 109.00 | Did Not Play |