| Position | Starters | Proteam | TW | PPG | Total | Breakdown |
|---|---|---|---|---|---|---|
| QB | Patrick Mahomes | KC | 24.86 | 25.59 | 409.46 | 259 Pass, 25 Rush, 2 TD |
| RB | Sony Michel | LAR | 17.4 | 8.21 | 131.40 | 74 Rush, 25 Receiving, 3 Rec, 1 TD |
| RB | Javonte Williams | Den | 3.7 | 11.06 | 177.00 | 30 Rush, 2 Receiving, 1 Rec |
| WR | Tyreek Hill | KC | 7.2 | 15.08 | 241.30 | 2 Rush, 40 Receiving, 6 Rec |
| WR | Jakobi Meyers | NE | 17.3 | 8.62 | 137.90 | 73 Receiving, 8 Rec, 1 TD |
| WR | Darnell Mooney | Chi | 16.4 | 10.04 | 160.60 | 69 Receiving, 7 Rec, 1 TD |
| TE | Pat Freiermuth | Pit | 4.7 | 7.63 | 114.40 | 22 Receiving, 5 Rec |
| HB (RB) | Ezekiel Elliott | Dal | 3.5 | 13.75 | 220.06 | 16 Rush, 14 Receiving, 1 Rec |
| PK | Greg Zuerlein | Dal | 2.0 | 8.27 | 124.00 | 2 XP |
| DL | Nick Bosa | SF | 1.0 | 7.50 | 120.00 | 1 Assist |
| DL | Marcus Davenport | NO | 5.0 | 7.60 | 76.00 | 2 Assists, 1 Fum Rcvy |
| DL | Myles Garrett | Cle | 1.0 | 7.88 | 126.00 | 1 Tackle |
| LB | Jordyn Brooks | Sea | 10.0 | 11.06 | 177.00 | 5 Tackles, 5 Assists |
| LB | T.J. Edwards | Phi | 13.0 | 9.13 | 146.00 | 7 Tackles, 6 Assists |
| LB | Darius Leonard | Ind | 16.0 | 11.53 | 173.00 | 6 Tackles, 1 Assist, 1 Int, 1 FF, 1 PD |
| CB | Trevon Diggs | Dal | 3.0 | 8.75 | 140.00 | 3 Tackles |
| S | Jalen Thompson | Ari | 6.0 | 8.19 | 131.00 | 3 Tackles, 3 Assists |
| Position | 1st Backups | Proteam | TW | PPG | Total | Breakdown |
| QB | Davis Mills | Hou | 0(10.92) | 13.06 | 156.72 | 163 Pass, 4 Rush, 1 TD, 1 Int |
| RB | Saquon Barkley | NYG | 0(10.2) | 10.23 | 122.70 | 102 Rush |
| WR | Byron Pringle | KC | 0(5.0) | 6.17 | 98.70 | 35 Receiving, 3 Rec |
| TE | Brevin Jordan | Hou | 0(1.4) | 5.72 | 45.80 | 9 Receiving, 1 Rec |
| HB (RB) | Jaret Patterson | Was | 0(18.3) | 2.90 | 46.40 | 57 Rush, 41 Receiving, 5 Rec, 1 TD |
| DL | Javon Hargrave | Phi | 0(5.0) | 6.13 | 98.00 | 2 Tackles, 3 Assists |
| LB | Micah Parsons | Dal | 0(5.0) | 9.19 | 147.00 | 4 Tackles, 1 Assist |
| CB | M.J. Stewart | Cle | 0(8.0) | 3.25 | 52.00 | 4 Tackles, 2 Assists, 2 PD |
| Position | 2nd Backups | Proteam | TW | PPG | Total | Breakdown |
| RB | AJ Dillon | GB | 0(21.3) | 10.15 | 162.40 | 63 Rush, 20 Receiving, 2 Rec, 2 TD |
| WR | Marquez Callaway | NO | 0(12.7) | 8.05 | 128.80 | 97 Receiving, 6 Rec |
| HB (WR) | Nico Collins | Hou | 0(4.5) | 4.53 | 58.90 | 35 Receiving, 2 Rec |
| LB | Quincy Williams | NYJ | 0(7.0) | 6.63 | 106.00 | 2 Tackles, 5 Assists |
| Offense = 97.06 Defense = 55 Total = 152.06 | ||||||
| Position | Bench | Proteam | TW | PPG | Total | Breakdown |
| RB | D'Onta Foreman | Ten | 0(19.2) | 5.43 | 81.50 | 132 Rush, 1 TD |
| RB | Khalil Herbert | Chi | 0(0.9) | 4.43 | 70.80 | 9 Rush |
| RB | Ke'Shawn Vaughn | TB | 0(5.5) | 2.14 | 23.50 | 31 Rush, 14 Receiving, 2 Rec |
| WR | Jerry Jeudy | Den | DNP | 6.89 | 62.00 | Did Not Play |
| Position | Injured Reserve | Proteam | TW | PPG | Total | Breakdown |
| WR | Calvin Ridley | Atl | DNP | 11.12 | 55.60 | Did Not Play |