| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | Justin Herbert | LAC | 21.68 | 26.52 | 424.34 | 237 Pass, 2 Rush, 2 TD |
| RB | Rex Burkhead | Hou | 10.90 | 5.58 | 83.70 | 47 Rush, 32 Receiving, 6 Rec |
| RB | Austin Ekeler | LAC | 18.70 | 19.03 | 285.40 | 58 Rush, 54 Receiving, 3 Rec, 1 TD |
| WR | Justin Jefferson | Min | 8.80 | 16.11 | 257.80 | 58 Receiving, 6 Rec |
| WR | Deebo Samuel | SF | 15.70 | 18.37 | 275.50 | 19 Rush, 63 Receiving, 3 Rec, 1 TD |
| WR | DeVonta Smith | Phi | 6.90 | 9.31 | 149.00 | 54 Receiving, 3 Rec |
| TE | Rob Gronkowski | TB | 15.00 | 11.50 | 126.50 | 115 Receiving, 7 Rec |
| HB | Mark Andrews | Bal | 11.90 | 14.69 | 235.10 | 89 Receiving, 6 Rec |
| PK | Justin Tucker | Bal | 15.00 | 9.69 | 155.00 | 2 FG(<40), 2 FG(40-49), 1 XP |
| DL | Sam Hubbard | Cin | 5.00 | 6.44 | 103.00 | 2 Tackles, 3 Assists |
| DL | Yannick Ngakoue | LV | 5.00 | 4.75 | 76.00 | 1 Tackle, 1.0 Sack |
| DL | Darrell Taylor | Sea | 2.00 | 4.20 | 63.00 | 2 Tackles |
| LB | Deion Jones | Atl | 8.00 | 10.00 | 150.00 | 6 Tackles, 2 Assists |
| LB | Denzel Perryman | LV | 10.00 | 11.07 | 155.00 | 5 Tackles, 2 Assists, 1 FF |
| LB | Devin White | TB | 2.00 | 9.00 | 144.00 | 2 Tackles |
| CB | JC Jackson | NE | 10.00 | 7.69 | 123.00 | 4 Tackles, 1 Int, 1 PD |
| S | Harrison Smith | Min | 8.00 | 9.64 | 135.00 | 5 Tackles, 3 Assists |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Derek Carr | LV | 0(12.20) | 18.04 | 288.62 | 255 Pass, 1 TD, 2 Int |
| RB | Justin Jackson | LAC | 0(7.60) | 5.71 | 74.20 | 41 Rush, 20 Receiving, 3 Rec |
| WR | Kendrick Bourne | NE | 0(11.80) | 9.46 | 151.30 | 17 Rush, 76 Receiving, 5 Rec |
| TE | Cameron Brate | TB | 0(7.50) | 3.83 | 61.30 | 5 Receiving, 2 Rec, 1 TD |
| RB | Kareem Hunt | Cle | DNP | 12.38 | 99.00 | Did Not Play |
| PK | Chris Boswell | Pit | 0(17.00) | 9.25 | 148.00 | 2 FG(<40), 1 FG(40-49), 1 FG(50-59), 2 XP |
| DL | Dante Fowler | Atl | 0(3.00) | 4.77 | 62.00 | 2 Tackles, 1 Assist |
| LB | Kyzir White | LAC | 0(11.00) | 9.75 | 156.00 | 5 Tackles, 6 Assists |
| CB | A.J. Terrell | Atl | 0(17.00) | 7.40 | 111.00 | 6 Tackles, 1 Assist, 1.0 Sack, 1 Int, 1 PD |
| S | Khari Willis | Ind | 0(3.00) | 7.90 | 79.00 | 3 Tackles |
| Pos. | 2nd Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Kirk Cousins | Min | DNP | 22.70 | 340.44 | Did Not Play |
| RB | Latavius Murray | Bal | 0(3.10) | 5.97 | 77.60 | 31 Rush |
| WR | Marquez Callaway | NO | 0(12.70) | 8.05 | 128.80 | 97 Receiving, 6 Rec |
| RB | Jeff Wilson | SF | 0 | 6.00 | 48.00 | Played, No Stats |
| Offense = 124.58 Defense = 50 Total = 174.58 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| WR | Kenny Golladay | NYG | 0.00 | 5.15 | 66.90 | Played, No Stats |
| WR | Rondale Moore | Ari | DNP | 5.94 | 83.10 | Did Not Play |