| Round | Overall | Player |
|---|---|---|
| 1 | 3rd | RB Joseph Addai Ind |
| 2 | 22nd | RB Marshawn Lynch Buf |
| 3 | 27th | QB Drew Brees NO |
| 4 | 46th | WR Andre Johnson Hou |
| 5 | 51st | RB Brandon Jackson GB |
| 6 | 70th | TE Kellen Winslow Jr. Cle |
| 7 | 75th | WR Deion Branch Sea |
| 8 | 94th | LB Lance Briggs Chi |
| 9 | 99th | S Bob Sanders Ind |
| 10 | 118th | WR Anthony Gonzalez Ind |
| 11 | 123rd | WR Dwayne Jarrett Car |
| 12 | 142nd | DL Tamba Hali KC |
| 13 | 147th | LB Lofa Tatupu Sea |
| 14 | 166th | RB Vernand Morency GB |
| 15 | 171st | DL Kyle Vanden Bosch Ten |
| 16 | 190th | QB J.P. Losman Buf |
| 17 | 195th | PK Nate Kaeding SD |
| 18 | 214th | TE Dallas Clark Ind |
| 19 | 219th | WR Eddie Kennison KC |
| 20 | 238th | LB D.J. Williams Den |
| 21 | 243rd | CB Antoine Bethea Ind |
| 22 | 262nd | DL Cory Redding Det |
| 23 | 267th | LB Thomas Howard Oak |
| 24 | 286th | RB DeDe Dorsey Ind |
| 25 | 291st | QB Brodie Croyle KC |
| 26 | 310th | S Stuart Schweigert Oak |
| 27 | 315th | CB Anthony Henry Dal |
| 28 | 334th | PK Mike Nugent NYJ |