| Round | Overall | Player |
|---|---|---|
| 1 | 12th | RB Laurence Maroney NE |
| 2 | 13th | RB Adrian Peterson Min |
| 3 | 36th | TE Antonio Gates SD |
| 4 | 37th | WR Calvin Johnson Det |
| 5 | 60th | WR Donald Driver GB |
| 6 | 61st | WR Hines Ward Pit |
| 7 | 84th | RB Kevin Jones Det |
| 8 | 85th | QB Jay Cutler Den |
| 9 | 108th | CB Ronde Barber TB |
| 10 | 109th | LB Paul Posluszny F/A |
| 11 | 132nd | LB Derrick Johnson KC |
| 12 | 133rd | QB Jake Delhomme F/A |
| 13 | 156th | WR Robert Meachem NO |
| 14 | 157th | DL Dwight Freeney Ind |
| 15 | 180th | S Troy Polamalu Pit |
| 16 | 181st | S Roy Williams Dal |
| 17 | 204th | WR Dwayne Bowe KC |
| 18 | 205th | RB Sammy Morris NE |
| 19 | 228th | RB Adrian Peterson Chi |
| 20 | 229th | DL Adewale Ogunleye Chi |
| 21 | 252nd | PK Olindo Mare NO |
| 22 | 253rd | DL Amobi Okoye Hou |
| 23 | 276th | CB Dunta Robinson Hou |
| 24 | 277th | LB Kamerion Wimbley Cle |
| 25 | 300th | CB Walt Harris SF |
| 26 | 301st | RB Garrett Wolfe Chi |
| 27 | 324th | PK Matt Stover Bal |
| 28 | 325th | WR Bobby Wade Min |