| Round | Overall | Player |
|---|---|---|
| 1 | 11th | RB Frank Gore SF |
| 2 | 14th | QB Drew Brees NO |
| 3 | 35th | RB Reggie Bush NO |
| 4 | 38th | WR Torry Holt StL |
| 5 | 59th | LB Jon Beason Car |
| 6 | 62nd | LB Nick Barnett GB |
| 7 | 83rd | WR Roddy White Atl |
| 8 | 86th | TE Dallas Clark Ind |
| 9 | 107th | RB Rudi Johnson Det |
| 10 | 110th | S Bob Sanders Ind |
| 11 | 131st | DL Will Smith NO |
| 12 | 134th | LB Curtis Lofton Atl |
| 13 | 155th | RB Deuce McAllister NO |
| 14 | 158th | S LaRon Landry Was |
| 15 | 179th | WR Robert Meachem NO |
| 16 | 182nd | WR Drew Bennett StL |
| 17 | 203rd | CB Antoine Winfield Min |
| 18 | 206th | DL Dwight Freeney Ind |
| 19 | 227th | RB DeShaun Foster SF |
| 20 | 230th | PK Adam Vinatieri Ind |
| 21 | 251st | WR James Hardy Buf |
| 22 | 254th | LB Donnie Edwards KC |
| 23 | 275th | TE Dustin Keller NYJ |
| 24 | 278th | CB Ivan Taylor Pit |
| 25 | 299th | LB Channing Crowder Mia |
| 26 | 302nd | QB Kyle Orton Chi |
| 27 | 323rd | PK Jeff Reed Pit |
| 28 | 326th | RB Shaun Alexander Was |