| Round | Overall | Player |
|---|---|---|
| 1 | 7th | RB Frank Gore SF |
| 2 | 18th | WR Miles Austin Dal |
| 3 | 31st | WR Greg Jennings GB |
| 4 | 42nd | RB Jonathan Stewart Car |
| 5 | 55th | TE Vernon Davis SF |
| 6 | 66th | RB Felix Jones Dal |
| 7 | 79th | WR Jeremy Maclin Phi |
| 8 | 90th | LB Paul Posluszny Buf |
| 9 | 103rd | QB Brett Favre Ret |
| 10 | 114th | LB Brian Cushing Hou |
| 11 | 127th | RB Justin Forsett Sea |
| 12 | 138th | WR Kenny Britt Ten |
| 13 | 151st | RB Laurence Maroney Den |
| 14 | 162nd | QB Jason Campbell Oak |
| 15 | 175th | WR Nate Burleson Det |
| 16 | 186th | S Dashon Goldson SF |
| 17 | 199th | WR Sidney Rice Sea |
| 18 | 210th | DL Jay Ratliff Dal |
| 19 | 223rd | CB Cortland Finnegan Ten |
| 20 | 234th | RB Ryan Torain Was |
| 21 | 247th | PK Matt Prater Den |
| 22 | 258th | RB Marshawn Lynch Sea |
| 23 | 271st | LB Aaron Curry Sea |
| 24 | 282nd | RB Tashard Choice Dal |
| 25 | 295th | QB Trent Edwards Jac |
| 26 | 306th | DL Chris Kelsay Buf |
| 27 | 319th | TE Shawn Nelson Buf |
| 28 | 330th | DL Kelly Gregg Bal |