| Round | Overall | Player |
|---|---|---|
| 1 | 10th | RB Ryan Mathews SD |
| 2 | 15th | WR Calvin Johnson Det |
| 3 | 34th | RB Arian Foster Hou |
| 4 | 39th | TE Jermichael Finley GB |
| 5 | 58th | RB Ahmad Bradshaw NYG |
| 6 | 63rd | DL Justin Tuck NYG |
| 7 | 82nd | RB Michael Bush Oak |
| 8 | 87th | WR T.J. Houshmandzadeh Bal |
| 9 | 106th | QB Carson Palmer Cin |
| 10 | 111th | WR Devin Aromashodu Chi |
| 11 | 130th | LB Jerod Mayo NE |
| 12 | 135th | WR Jabar Gaffney Den |
| 13 | 154th | QB Matt Cassel KC |
| 14 | 159th | WR Mike Williams Sea |
| 15 | 178th | CB Antoine Winfield Min |
| 16 | 183rd | RB Steve Slaton Hou |
| 17 | 202nd | DL Mathias Kiwanuka NYG |
| 18 | 207th | LB Lawrence Timmons Pit |
| 19 | 226th | S Quintin Mikell Phi |
| 20 | 231st | LB Dan Connor Car |
| 21 | 250th | S Donte Whitner Buf |
| 22 | 255th | TE Ben Watson Cle |
| 23 | 274th | LB Clint Session Ind |
| 24 | 279th | WR Eric Decker Den |
| 25 | 298th | DL Derrick Harvey Jac |
| 26 | 303rd | S Sean Jones TB |
| 27 | 322nd | WR Jordy Nelson GB |
| 28 | 327th | PK Sebastian Janikowski Oak |