| Round | Overall | Player |
|---|---|---|
| 1 | 11th | RB DeAngelo Williams Car |
| 2 | 14th | RB Shonn Greene NYJ |
| 3 | 35th | QB Matt Schaub Hou |
| 4 | 38th | DL Jared Allen Min |
| 5 | 59th | QB Kevin Kolb Ari |
| 6 | 62nd | WR Steve Smith NYG |
| 7 | 83rd | WR Mike Sims-Walker Jac |
| 8 | 86th | TE Tony Gonzalez Atl |
| 9 | 107th | RB Donald Brown Ind |
| 10 | 110th | WR Bernard Berrian Min |
| 11 | 131st | DL Robert Mathis Ind |
| 12 | 134th | S Bernard Pollard Hou |
| 13 | 155th | LB Jonathan Vilma NO |
| 14 | 158th | WR Dez Bryant Dal |
| 15 | 179th | WR Lee Evans Buf |
| 16 | 182nd | RB Fred Jackson Buf |
| 17 | 203rd | DL Antwan Odom Cin |
| 18 | 206th | LB LaMarr Woodley Pit |
| 19 | 227th | LB Clay Matthews GB |
| 20 | 230th | PK David Akers Phi |
| 21 | 251st | WR Devery Henderson NO |
| 22 | 254th | RB Kareem Huggins TB |
| 23 | 275th | LB Bradie James Dal |
| 24 | 278th | RB Mike Bell Cle |
| 25 | 299th | DL David Bowens Cle |
| 26 | 302nd | CB Dominique Rodgers-Cromartie Ari |
| 27 | 323rd | WR Mario Manningham NYG |
| 28 | 326th | S Tanard Jackson TB |