| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | RB Chris Johnson Ten |
| 2 | 23rd | QB Philip Rivers SD |
| 3 | 26th | WR Miles Austin Dal |
| 4 | 47th | TE Antonio Gates SD |
| 5 | 50th | WR Steve Smith Car |
| 6 | 71st | RB Matt Forte Chi |
| 7 | 74th | RB C.J. Spiller Buf |
| 8 | 95th | RB Marion Barber Chi |
| 9 | 98th | QB Ben Roethlisberger Pit |
| 10 | 119th | RB Donald Brown Ind |
| 11 | 122nd | DL Aaron Kampman Jac |
| 12 | 143rd | LB Demarcus Ware Dal |
| 13 | 146th | WR Bernard Berrian Min |
| 14 | 167th | RB Chester Taylor Chi |
| 15 | 170th | DL Osi Umenyiora NYG |
| 16 | 191st | S Oshiomogho Atogwe StL |
| 17 | 194th | PK Garrett Hartley NO |
| 18 | 215th | WR Devery Henderson NO |
| 19 | 218th | RB Tashard Choice Dal |
| 20 | 239th | WR Laurent Robinson SD |
| 21 | 242nd | LB Chad Greenway Min |
| 22 | 263rd | RB Mike Bell Cle |
| 23 | 266th | QB Matt Moore Car |
| 24 | 287th | LB Stephen Cooper SD |
| 25 | 290th | CB Johnathan Joseph Cin |
| 26 | 311th | RB Marshawn Lynch Sea |
| 27 | 314th | LB Gary Brackett Ind |
| 28 | 335th | DL Connor Barwin Hou |