| Round | Overall | Player |
|---|---|---|
| 1 | 11th | RB Steven Jackson StL |
| 2 | 14th | RB DeAngelo Williams Car |
| 3 | 35th | QB Tony Romo Dal |
| 4 | 38th | TE Jermichael Finley GB |
| 5 | 59th | WR Hakeem Nicks NYG |
| 6 | 62nd | WR Dwayne Bowe KC |
| 7 | 83rd | DL Trent Cole Phi |
| 8 | 86th | RB Reggie Bush Mia |
| 9 | 107th | LB Ray Lewis Bal |
| 10 | 110th | LB Karlos Dansby Mia |
| 11 | 131st | RB Darren McFadden Oak |
| 12 | 134th | WR Lee Evans Buf |
| 13 | 155th | WR Devin Hester Chi |
| 14 | 158th | RB Kareem Huggins TB |
| 15 | 179th | QB Vince Young Ten |
| 16 | 182nd | DL Trevor Scott Oak |
| 17 | 203rd | RB Peyton Hillis Cle |
| 18 | 206th | S Patrick Chung NE |
| 19 | 227th | CB Malcolm Jenkins NO |
| 20 | 230th | RB Leon Washington Sea |
| 21 | 251st | TE Todd Heap Ari |
| 22 | 254th | LB Stewart Bradley Phi |
| 23 | 275th | PK Neil Rackers Hou |
| 24 | 278th | WR Louis Murphy Oak |
| 25 | 299th | RB Correll Buckhalter Den |
| 26 | 302nd | S Adrian Wilson Ari |
| 27 | 323rd | CB Brandon Flowers KC |
| 28 | 326th | DL Ndamukong Suh Det |