| Round | Overall | Player |
|---|---|---|
| 1 | 6th | QB Drew Brees NO |
| 2 | 19th | RB Pierre Thomas Jr. NO |
| 3 | 30th | RB LeSean McCoy Phi |
| 4 | 43rd | WR Malcom Floyd SD |
| 5 | 54th | WR Percy Harvin Min |
| 6 | 67th | TE Tony Gonzalez Atl |
| 7 | 78th | RB Carnell Williams StL |
| 8 | 91st | WR Santana Moss Was |
| 9 | 102nd | WR Jacoby Jones Hou |
| 10 | 115th | LB Lance Briggs Chi |
| 11 | 126th | LB Brian Cushing Hou |
| 12 | 139th | WR Nate Burleson Det |
| 13 | 150th | DL David Bowens Cle |
| 14 | 163rd | S Eric Berry KC |
| 15 | 174th | CB Cortland Finnegan Ten |
| 16 | 187th | S Troy Polamalu Pit |
| 17 | 198th | RB Julius Jones NO |
| 18 | 211th | DL Robert Ayers Den |
| 19 | 222nd | WR Danny Amendola StL |
| 20 | 235th | QB Matt Hasselbeck Sea |
| 21 | 246th | TE Rob Gronkowski NE |
| 22 | 259th | RB Bernard Scott Cin |
| 23 | 270th | LB James Farrior Pit |
| 24 | 283rd | CB Jabari Greer NO |
| 25 | 294th | PK David Buehler Dal |
| 26 | 307th | WR Mohamed Massaquoi Cle |
| 27 | 318th | WR Steve Breaston KC |
| 28 | 331st | PK Josh Brown StL |