| Round | Overall | Player |
|---|---|---|
| 1 | 12th | RB Rashard Mendenhall Pit |
| 2 | 13th | RB Ryan Mathews SD |
| 3 | 36th | WR Steve Smith NYG |
| 4 | 37th | QB Matthew Stafford Det |
| 5 | 60th | TE Brent Celek Phi |
| 6 | 61st | WR Johnny Knox Chi |
| 7 | 84th | QB Jay Cutler Chi |
| 8 | 85th | DL Julius Peppers Chi |
| 9 | 108th | QB Brett Favre Ret |
| 10 | 109th | LB James Harrison Pit |
| 11 | 132nd | DL Tamba Hali KC |
| 12 | 133rd | LB Lawrence Timmons Pit |
| 13 | 156th | RB Michael Bush Oak |
| 14 | 157th | TE Heath Miller Pit |
| 15 | 180th | RB Darren Sproles NO |
| 16 | 181st | WR Lance Moore NO |
| 17 | 204th | WR Mario Manningham NYG |
| 18 | 205th | S Louis Delmas Det |
| 19 | 228th | LB Clint Session Ind |
| 20 | 229th | WR Roy Williams Chi |
| 21 | 252nd | LB Aaron Curry Sea |
| 22 | 253rd | PK Lawrence Tynes NYG |
| 23 | 276th | S Earl Thomas Sea |
| 24 | 277th | WR Brian Hartline Mia |
| 25 | 300th | RB Jonathan Dwyer Pit |
| 26 | 301st | CB DeAngelo Hall Was |
| 27 | 324th | DL Everette Brown Car |
| 28 | 325th | CB Nate Clements SF |