| Round | Overall | Player |
|---|---|---|
| 1 | 4th | WR Calvin Johnson Det |
| 2 | 21st | WR Andre Johnson Hou |
| 3 | 28th | RB Jamaal Charles KC |
| 4 | 45th | QB Tony Romo Dal |
| 5 | 52nd | DL Jared Allen Min |
| 6 | 69th | QB Robert Griffin III Was |
| 7 | 76th | TE Vernon Davis SF |
| 8 | 93rd | RB Kevin Smith Det |
| 9 | 100th | RB Ryan Williams F/A |
| 10 | 117th | RB David Wilson NYG |
| 11 | 124th | DL Calais Campbell Ari |
| 12 | 141st | WR Justin Blackmon Jac |
| 13 | 148th | RB C.J. Spiller Buf |
| 14 | 165th | WR Anquan Boldin Bal |
| 15 | 172nd | LB DeMeco Ryans Phi |
| 16 | 189th | RB LeGarrette Blount TB |
| 17 | 196th | LB Nick Barnett Buf |
| 18 | 213th | TE Greg Olsen Car |
| 19 | 220th | PK Matt Bryant Atl |
| 20 | 237th | WR Kendall Wright Ten |
| 21 | 244th | RB Kendall Hunter F/A |
| 22 | 261st | RB Alex Green GB |
| 23 | 268th | S T.J. Ward Cle |
| 24 | 285th | WR Terrell Owens F/A |
| 25 | 292nd | DL Kyle Williams Buf |
| 26 | 309th | LB Rolando McClain Oak |
| 27 | 316th | CB Brandon Carr Dal |
| 28 | 333rd | S Harrison Smith Min |