| Round | Overall | Player |
|---|---|---|
| 1 | 7th | QB Drew Brees NO |
| 2 | 18th | RB Matt Forte Chi |
| 3 | 31st | WR Wesley Welker NE |
| 4 | 42nd | WR Dez Bryant Dal |
| 5 | 55th | RB Frank Gore SF |
| 6 | 66th | WR Vincent Jackson TB |
| 7 | 79th | RB Michael Bush Chi |
| 8 | 90th | RB Isaac Redman Pit |
| 9 | 103rd | RB DeAngelo Williams Car |
| 10 | 114th | QB Andy Dalton Cin |
| 11 | 127th | TE Tony Gonzalez Atl |
| 12 | 138th | S George Wilson Buf |
| 13 | 151st | LB Luke Kuechly Car |
| 14 | 162nd | LB Ray Lewis F/A |
| 15 | 175th | DL Charles Johnson Car |
| 16 | 186th | WR Santonio Holmes F/A |
| 17 | 199th | WR Sidney Rice Sea |
| 18 | 210th | DL Robert Quinn StL |
| 19 | 223rd | DL Quinton Coples NYJ |
| 20 | 234th | LB Kavell Conner Ind |
| 21 | 247th | CB Lardarius Webb F/A |
| 22 | 258th | TE Kellen Winslow Jr. F/A |
| 23 | 271st | WR Brian Quick StL |
| 24 | 282nd | CB Tramon Williams GB |
| 25 | 295th | S Quintin Mikell StL |
| 26 | 306th | PK Mike Nugent Cin |
| 27 | 319th | PK Robbie Gould F/A |
| 28 | 330th | RB Bernard Scott F/A |