| Round | Overall | Player |
|---|---|---|
| 1 | 9th | RB Darren McFadden Oak |
| 2 | 16th | RB Ryan Mathews SD |
| 3 | 33rd | WR Brandon Marshall Chi |
| 4 | 40th | WR Brandon Lloyd NE |
| 5 | 57th | QB Jay Cutler Chi |
| 6 | 64th | WR Marques Colston NO |
| 7 | 81st | WR Pierre Garcon Was |
| 8 | 88th | TE Brandon Pettigrew Det |
| 9 | 105th | LB Colin McCarthy Ten |
| 10 | 112th | DL Elvis Dumervil Den |
| 11 | 129th | QB Tim Tebow NYJ |
| 12 | 136th | WR Robert Meachem SD |
| 13 | 153rd | DL J.J. Watt Hou |
| 14 | 160th | LB Donald Butler SD |
| 15 | 177th | LB Stephen Tulloch Det |
| 16 | 184th | DL Ndamukong Suh Det |
| 17 | 201st | RB Daniel Thomas Mia |
| 18 | 208th | S Bernard Pollard Bal |
| 19 | 225th | PK Jason Hanson Det |
| 20 | 232nd | TE Coby Fleener Ind |
| 21 | 249th | RB Robert Turbin Sea |
| 22 | 256th | LB Dave Harris NYJ |
| 23 | 273rd | RB Evan Royster Was |
| 24 | 280th | DL Aaron Maybin NYJ |
| 25 | 297th | CB Malcolm Jenkins NO |
| 26 | 304th | LB Melvin Ingram SD |
| 27 | 321st | WR Stephen Hill NYJ |
| 28 | 328th | WR Mohamed Massaquoi Cle |