| Round | Overall | Player |
|---|---|---|
| 1 | 9th | WR Calvin Johnson Det |
| 2 | 16th | WR Andre Johnson Hou |
| 3 | 33rd | RB Michael Turner Atl |
| 4 | 40th | QB Philip Rivers SD |
| 5 | 57th | RB Ahmad Bradshaw NYG |
| 6 | 64th | WR Antonio Brown Pit |
| 7 | 81st | RB Cedric Benson F/A |
| 8 | 88th | RB Kevin Smith Det |
| 9 | 105th | LB Desmond Bishop F/A |
| 10 | 112th | DL Calais Campbell Ari |
| 11 | 129th | TE Tony Gonzalez Atl |
| 12 | 136th | TE Jermaine Gresham Cin |
| 13 | 153rd | S Morgan Burnett GB |
| 14 | 160th | DL Haloti Ngata Bal |
| 15 | 177th | LB Demarcus Ware Dal |
| 16 | 184th | LB Ray Lewis F/A |
| 17 | 201st | WR Jonathan Baldwin KC |
| 18 | 208th | QB Mark Sanchez NYJ |
| 19 | 225th | WR Randall Cobb GB |
| 20 | 232nd | RB Alex Green GB |
| 21 | 249th | S Earl Thomas Sea |
| 22 | 256th | PK Randy Bullock Hou |
| 23 | 273rd | RB Pierre Thomas Jr. NO |
| 24 | 280th | LB LaMarr Woodley Pit |
| 25 | 297th | DL Chris Long StL |
| 26 | 304th | WR Santana Moss Was |
| 27 | 321st | CB Chris Houston Det |
| 28 | 328th | DL Marcell Dareus Buf |