| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | RB Trent Richardson Ind |
| 2 | 23rd | WR Randall Cobb F/A |
| 3 | 26th | RB Lamar Miller Mia |
| 4 | 47th | RB Giovani Bernard Cin |
| 5 | 50th | WR Lance Moore NO |
| 6 | 71st | QB Russell Wilson Sea |
| 7 | 74th | WR Mike Williams F/A |
| 8 | 95th | TE Tony Gonzalez Atl |
| 9 | 98th | WR Josh Gordon Cle |
| 10 | 119th | RB Andre Brown NYG |
| 11 | 122nd | LB Paul Posluszny Jac |
| 12 | 143rd | LB Jerrell Freeman Ind |
| 13 | 146th | CB Richard Sherman Sea |
| 14 | 167th | S William Moore Atl |
| 15 | 170th | DL Geno Atkins F/A |
| 16 | 191st | RB Shonn Greene Ten |
| 17 | 194th | WR Brian Hartline Mia |
| 18 | 215th | TE Owen Daniels F/A |
| 19 | 218th | LB Dannell Ellerbe Mia |
| 20 | 239th | QB Brandon Weeden Cle |
| 21 | 242nd | RB Mike James F/A |
| 22 | 263rd | S Ryan Clark Pit |
| 23 | 266th | WR Darrius Heyward-Bey Ind |
| 24 | 287th | PK David Akers Det |
| 25 | 290th | DL Brian Robison Min |
| 26 | 311th | RB Mikel LeShoure Det |
| 27 | 314th | PK Rob Bironas Ten |
| 28 | 335th | CB Glover Quin Det |