| Round | Overall | Player |
|---|---|---|
| 1 | 7th | RB Marshawn Lynch Sea |
| 2 | 18th | RB Matt Forte Chi |
| 3 | 31st | WR Roddy White Atl |
| 4 | 42nd | QB Colin Kaepernick SF |
| 5 | 55th | WR Reggie Wayne F/A |
| 6 | 66th | RB Giovani Bernard Cin |
| 7 | 79th | TE Jason Witten Dal |
| 8 | 90th | S Harrison Smith F/A |
| 9 | 103rd | WR Tavon Austin StL |
| 10 | 114th | DL Charles Johnson Car |
| 11 | 127th | LB Sean Lee Dal |
| 12 | 138th | QB Ben Roethlisberger Pit |
| 13 | 151st | TE Jordan Cameron Cle |
| 14 | 162nd | LB Clay Matthews GB |
| 15 | 175th | CB Tim Jennings Chi |
| 16 | 186th | WR Denarius Moore Oak |
| 17 | 199th | DL Robert Quinn StL |
| 18 | 210th | RB Michael Bush Chi |
| 19 | 223rd | LB Curtis Lofton NO |
| 20 | 234th | PK Blair Walsh Min |
| 21 | 247th | DL Ziggy Ansah Det |
| 22 | 258th | LB Arthur Brown Bal |
| 23 | 271st | WR Quinton Patton SF |
| 24 | 282nd | S Eric Reid SF |
| 25 | 295th | PK Rob Bironas Ten |
| 26 | 306th | QB Brandon Weeden Cle |
| 27 | 319th | WR Percy Harvin Sea |
| 28 | 330th | DL Chris Clemons Sea |