*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 14.30 | Week 16, 2020 | SF | @ARI@ARI | 3 Rush, 10 Receiving, 2 Rec, 2 TD |
| 2. | 13.10 | Week 03, 2021 | SF | GBGB | 14 Rush, 37 Receiving, 4 Rec, 1 TD |
| 3. | 11.70 | Week 05, 2018 | SF | AriAri | 12 Rush, 75 Receiving, 6 Rec |
| 4. | 11.00 | Week 03, 2014 | Bal | @Cle@Cle | 54 Receiving, 1 TD |
| 5. | 10.80 | Week 03, 2018 | SF | @KC@KC | 38 Receiving, 2 Rec, 1 TD |
| 6. | 10.60 | Week 05, 2023 | SF | DalDal | 26 Receiving, 4 Rec, 1 TD |
| 7. | 10.10 | Week 07, 2020 | SF | @NE@NE | 18 Rush, 18 Receiving, 1 Rec, 1 TD |
| 8. | 9.80 | Week 11, 2019 | SF | AriAri | 63 Receiving, 7 Rec |
| 9. | 9.00 | Week 05, 2015 | Bal | CleCle | 31 Receiving, 1 TD |
| 10. | 8.80 | Week 14, 2020 | SF | WASWAS | 3 Rush, 15 Receiving, 2 Rec, 1 TD |
| 11. | 8.70 | Week 13, 2022 | SF | MiaMia | 12 Receiving, 3 Rec, 1 TD |
| 12. | 8.00 | Week 16, 2016 | Bal | @Pit@Pit | 15 Rush, 10 Receiving, 1 TD |
| 12. | 8.00 | Week 15, 2015 | Bal | KCKC | 26 Receiving, 1 TD |
| 14. | 7.70 | Week 15, 2021 | SF | ATLATL | 6 Rush, 6 Receiving, 1 Rec, 1 TD |
| 14. | 7.70 | Week 15, 2019 | SF | AtlAtl | 1 Rush, 6 Receiving, 2 Rec, 1 TD |
| 16. | 7.60 | Week 13, 2020 | SF | BUFBUF | 5 Rush, 6 Receiving, 1 Rec, 1 TD |
| 17. | 7.10 | Week 05, 2020 | SF | MIAMIA | 11 Rush, 1 TD |
| 18. | 7.00 | Week 16, 2017 | SF | JacJac | 76 Receiving |
| 18. | 7.00 | Week 05, 2017 | SF | @Ind@Ind | 3 Rush, 14 Receiving, 1 TD |
| 18. | 7.00 | Week 17, 2015 | Bal | @Cin@Cin | 18 Receiving, 1 TD |
| 18. | 7.00 | Week 07, 2015 | Bal | @Ari@Ari | 15 Receiving, 1 TD |
| 22. | 6.60 | Week 03, 2019 | SF | PitPit | 51 Receiving, 3 Rec |
| 23. | 6.10 | Week 02, 2022 | SF | SeaSea | 1 Rush, 1 TD |
| 23. | 6.10 | Week 04, 2021 | SF | SEASEA | 41 Receiving, 4 Rec |
| 23. | 6.10 | Week 01, 2018 | SF | @Min@Min | 56 Receiving, 1 Rec |
| 26. | 6.00 | Week 16, 2021 | SF | @TEN@TEN | 45 Receiving, 3 Rec |
| 26. | 6.00 | Week 14, 2017 | SF | @Hou@Hou | 64 Receiving |
| 28. | 5.40 | Week 17, 2019 | SF | @Sea@Sea | 49 Receiving, 1 Rec |
| 29. | 5.30 | Week 06, 2022 | SF | @Atl@Atl | 33 Receiving, 4 Rec |
| 29. | 5.30 | Week 01, 2020 | SF | AriAri | 7 Rush, 41 Receiving, 1 Rec |
| 31. | 5.00 | Week 01, 2024 | SF | @NYJ@NYJ | 40 Receiving, 2 Rec |
| 31. | 5.00 | Week 05, 2021 | SF | @ARI@ARI | 35 Receiving, 3 Rec |
| 31. | 5.00 | Week 04, 2016 | Bal | OakOak | 56 Receiving |
| 31. | 5.00 | Week 16, 2015 | Bal | PitPit | 55 Receiving |
| 35. | 4.90 | Week 07, 2022 | SF | KCKC | 34 Receiving, 3 Rec |
| 35. | 4.90 | Week 04, 2022 | SF | LARLAR | 9 Rush, 35 Receiving, 1 Rec |
| 37. | 4.70 | Week 12, 2021 | SF | MINMIN | 37 Receiving, 2 Rec |
| 38. | 4.20 | Week 12, 2020 | SF | @LAR@LAR | 8 Rush, 24 Receiving, 2 Rec |
| 39. | 4.00 | Week 14, 2016 | Bal | @NE@NE | 46 Receiving |
| 39. | 4.00 | Week 10, 2015 | Bal | JacJac | 47 Receiving |
| 41. | 3.80 | Week 17, 2023 | SF | @Was@Was | 23 Receiving, 3 Rec |
| 42. | 3.70 | Week 05, 2022 | SF | @Car@Car | 27 Receiving, 2 Rec |
| 42. | 3.70 | Week 14, 2019 | SF | @NO@NO | 22 Receiving, 3 Rec |
| 44. | 3.60 | Week 15, 2023 | SF | @Ari@Ari | 26 Receiving, 2 Rec |
| 45. | 3.50 | Week 13, 2018 | SF | @Sea@Sea | 20 Receiving, 3 Rec |
| 45. | 3.50 | Week 06, 2018 | SF | @GB@GB | 30 Receiving, 3 Rec, 1 Fumb |
| 47. | 3.40 | Week 02, 2024 | SF | MinMin | 19 Receiving, 3 Rec |
| 47. | 3.40 | Week 18, 2022 | SF | AriAri | 3 Rush, 26 Receiving, 1 Rec |
| 47. | 3.40 | Week 15, 2020 | SF | @DAL@DAL | 4 Rush, 25 Receiving, 1 Rec |
| 50. | 3.10 | Week 13, 2021 | SF | @SEA@SEA | 21 Receiving, 2 Rec |