*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 13.00 | Week 06, 2017 | SF | @Was@Was | 7 Tackles, 2 Assists, 1.0 Sack |
| 2. | 11.00 | Week 02, 2021 | LV | @PIT@PIT | 2 Tackles, 2.0 Sacks, 1 PD |
| 3. | 10.00 | Week 16, 2017 | SF | JacJac | 5 Tackles, 1 Assist, 1.0 Sack |
| 4. | 9.00 | Week 03, 2021 | LV | MIAMIA | 1 Tackle, 3 Assists, 0.5 Sack, 1 FF |
| 4. | 9.00 | Week 04, 2017 | SF | @Ari@Ari | 5 Tackles, 1.0 Sack |
| 6. | 8.00 | Week 02, 2024 | NYJ | TenTen | 1 Tack , 2 Ass, 1.00 Sack, 1 PD |
| 7. | 7.00 | Week 15, 2023 | NYJ | @Mia@Mia | 2 Tackles, 1 Assist, 1.0 Sack |
| 7. | 7.00 | Week 10, 2023 | NYJ | @LV@LV | 1 Tackle, 2 Assists, 1.0 Sack |
| 7. | 7.00 | Week 17, 2022 | NYJ | @Sea@Sea | 3 Tackles, 2 Assists, 0.5 Sack |
| 7. | 7.00 | Week 02, 2019 | SF | @Cin@Cin | |
| 7. | 7.00 | Week 09, 2018 | SF | OakOak | 3 Tackles, 1.0 Sack |
| 12. | 6.00 | Week 14, 2023 | NYJ | HouHou | 2 Tackles, 1.0 Sack |
| 12. | 6.00 | Week 12, 2023 | NYJ | MiaMia | 1 Tackle, 3 Assists, 0.5 Sack |
| 12. | 6.00 | Week 02, 2023 | NYJ | @Dal@Dal | 2 Tackles, 1.0 Sack |
| 12. | 6.00 | Week 11, 2021 | LV | CINCIN | 2 Tackles, 1.0 Sack |
| 12. | 6.00 | Week 06, 2019 | SF | @LAR@LAR | 2 Tackles, 1.0 Sack |
| 17. | 5.00 | Week 02, 2022 | NYJ | @Cle@Cle | 2 Tackles, 3 Assists |
| 17. | 5.00 | Week 07, 2018 | SF | LARLAR | 3 Tackles, 2 Assists |
| 19. | 4.00 | Week 03, 2024 | NYJ | NE NE | 1 Tack, 1 Ass, 0.50 Sack |
| 19. | 4.00 | Week 01, 2024 | NYJ | @SF @SF | 3 Tack, 1 Ass |
| 19. | 4.00 | Week 13, 2023 | NYJ | AtlAtl | 1 Tackle, 3 Assists |
| 19. | 4.00 | Week 09, 2023 | NYJ | LACLAC | 2 Assists, 0.5 Sack |
| 19. | 4.00 | Week 12, 2022 | NYJ | ChiChi | 3 Tackles, 1 Assist |
| 19. | 4.00 | Week 13, 2021 | LV | WASWAS | 2 Tackles, 2 Assists |
| 19. | 4.00 | Week 12, 2021 | LV | @DAL@DAL | 3 Tackles, 1 Assist |
| 19. | 4.00 | Week 06, 2021 | LV | @DEN@DEN | 1 Tackle, 1 FF |
| 19. | 4.00 | Week 17, 2018 | SF | @LAR@LAR | 2 Tackles, 2 Assists |
| 19. | 4.00 | Week 16, 2018 | SF | ChiChi | 3 Tackles, 1 Assist |
| 19. | 4.00 | Week 17, 2017 | SF | @LAR@LAR | 1 Tackle, 1 Fum Rcvy |
| 19. | 4.00 | Week 02, 2017 | SF | @Sea@Sea | 4 Tackles |
| 31. | 3.00 | Week 10, 2021 | LV | KCKC | 3 Assists |
| 31. | 3.00 | Week 07, 2021 | LV | PHIPHI | 1 Tackle, 2 Assists |
| 31. | 3.00 | Week 04, 2021 | LV | @LAC@LAC | 2 Assists, 1 PD |
| 31. | 3.00 | Week 15, 2017 | SF | TenTen | 2 Tackles, 1 Assist |
| 35. | 2.00 | Week 17, 2023 | NYJ | @Cle@Cle | 1 Tackle, 1 Assist |
| 35. | 2.00 | Week 06, 2023 | NYJ | PhiPhi | 2 Assists |
| 35. | 2.00 | Week 03, 2023 | NYJ | NENE | 2 Tackles |
| 35. | 2.00 | Week 16, 2022 | NYJ | JacJac | 2 Tackles |
| 35. | 2.00 | Week 07, 2022 | NYJ | @Den@Den | 1 Tackle, 1 Assist |
| 35. | 2.00 | Week 16, 2021 | LV | DENDEN | 1 Tackle, 1 Assist |
| 35. | 2.00 | Week 14, 2021 | LV | @KC@KC | 1 Tackle, 1 Assist |
| 35. | 2.00 | Week 09, 2021 | LV | @NYG@NYG | 1 Tackle, 1 Assist |
| 35. | 2.00 | Week 02, 2020 | SF | @NYJ@NYJ | 2 Assists |
| 35. | 2.00 | Week 17, 2019 | SF | @Sea@Sea | 2 Tackles |
| 35. | 2.00 | Week 08, 2019 | SF | CarCar | 1 Tackle, 1 Assist |
| 35. | 2.00 | Week 07, 2019 | SF | @Was@Was | 2 Tackles |
| 35. | 2.00 | Week 03, 2019 | SF | PitPit | 2 Tackles |
| 35. | 2.00 | Week 15, 2018 | SF | SeaSea | 2 Tackles |
| 35. | 2.00 | Week 13, 2018 | SF | @Sea@Sea | 2 Tackles |
| 35. | 2.00 | Week 12, 2018 | SF | @TB@TB | 2 Tackles |