*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 21.00 | Week 01, 2002 * | SF | @NYG@NYG | 13 Tackles, 4 Assists, 1.0 Sack |
| 2. | 14.00 | Week 10, 2008 | Den | @Cle@Cle | 12 Tackles, 1 Assist, 1 PD |
| 3. | 13.00 | Week 09, 2004 | SF | SeaSea | 6 Tackles, 1 Assist, 1.0 Sack, 2 PD |
| 3. | 13.00 | Week 08, 2004 | SF | @Chi@Chi | 5 Tackles, 2.0 Sacks |
| 3. | 13.00 | Week 06, 2004 | SF | @NYJ@NYJ | 11 Tackles, 2 Assists |
| 6. | 12.00 | Week 09, 2008 | Den | MiaMia | 5 Tackles, 4 Assists, 3 PD |
| 6. | 12.00 | Week 13, 2004 | SF | @StL@StL | 6 Tackles, 1 FF, 1 Fum Rcvy |
| 6. | 12.00 | Week 04, 2001 | SF | CarCar | 8 Tackles, 4 Assists |
| 9. | 11.00 | Week 11, 2008 | Den | @Atl@Atl | 8 Tackles, 2 Assists, 1 PD |
| 9. | 11.00 | Week 07, 2008 | Den | @NE@NE | 4 Tackles, 4 Assists, 0.5 Sack, 1 PD |
| 9. | 11.00 | Week 14, 2001 | SF | MiaMia | 7 Tackles, 2 Assists, 0.5 Sack |
| 12. | 10.00 | Week 13, 2008 | Den | @NYJ@NYJ | 8 Tackles, 1 Assist, 1 PD |
| 12. | 10.00 | Week 17, 2001 | SF | @NO@NO | 2 Tackles, 1 Int, 1 Fum Rcvy |
| 14. | 9.00 | Week 17, 2008 | Den | @SD@SD | 7 Tackles, 2 Assists |
| 14. | 9.00 | Week 05, 2004 | SF | AriAri | 2 Tackles, 1 Int2 PD |
| 14. | 9.00 | Week 08, 2003 | SF | @Ari@Ari | 8 Tackles, 1 Assist |
| 14. | 9.00 | Week 07, 2003 | SF | TBTB | 3 Tackles, 1 FF, 1 Fum Rcvy |
| 18. | 8.00 | Week 16, 2008 | Den | BufBuf | 4 Tackles, 2 Assists, 2 PD |
| 18. | 8.00 | Week 12, 2008 | Den | OakOak | 6 Tackles, 2 Assists |
| 18. | 8.00 | Week 10, 2004 | SF | CarCar | 4 Tackles, 1 FF, 1 PD |
| 18. | 8.00 | Week 01, 2004 | SF | AtlAtl | 2 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| 18. | 8.00 | Week 09, 2003 | SF | StLStL | 3 Tackles, 1 Assist, 1.0 Sack |
| 18. | 8.00 | Week 03, 2003 | SF | CleCle | 7 Tackles, 1 PD |
| 18. | 8.00 | Week 15, 2001 | SF | PhiPhi | 6 Tackles, 2 Assists |
| 18. | 8.00 | Week 12, 2001 | SF | BufBuf | 2 Tackles, 1 Assist, 1 Int |
| 26. | 7.00 | Week 03, 2008 | Den | NONO | 4 Tackles, 3 Assists |
| 26. | 7.00 | Week 01, 2003 | SF | ChiChi | 2 Tackles, 1.0 Sack, 1 PD |
| 26. | 7.00 | Week 02, 2002 | SF | DenDen | 5 Tackles, 2 Assists |
| 29. | 6.00 | Week 14, 2008 | Den | KCKC | 4 Tackles, 1 Assist, 1 PD |
| 29. | 6.00 | Week 01, 2008 | Den | @Oak@Oak | 5 Tackles, 1 Assist |
| 29. | 6.00 | Week 01, 2005 | SF | StLStL | 2 Tackles, 4 Assists |
| 29. | 6.00 | Week 12, 2004 | SF | MiaMia | 4 Tackles, 2 PD |
| 29. | 6.00 | Week 06, 2003 | SF | @Sea@Sea | 6 Tackles |
| 29. | 6.00 | Week 11, 2001 | SF | @Ind@Ind | 4 Tackles, 2 Assists |
| 35. | 5.00 | Week 15, 2008 | Den | @Car@Car | 4 Tackles, 1 PD |
| 35. | 5.00 | Week 02, 2005 | SF | @Phi@Phi | 4 Tackles, 1 Assist |
| 35. | 5.00 | Week 04, 2003 | SF | @Min@Min | 4 Tackles, 1 Assist |
| 35. | 5.00 | Week 02, 2003 | SF | @StL@StL | 1 Tackle, 1.0 Sack |
| 39. | 4.00 | Week 01, 2010 | Ten | OakOak | 2 Tackles, 2 Assists |
| 39. | 4.00 | Week 05, 2008 | Den | TBTB | 2 Tackles, 2 Assists |
| 39. | 4.00 | Week 14, 2006 | TB | AtlAtl | 1 Tackle, 1 FF |
| 39. | 4.00 | Week 12, 2006 | TB | @Dal@Dal | 3 Tackles, 1 Assist |
| 39. | 4.00 | Week 15, 2004 | SF | WasWas | 4 Tackles |
| 39. | 4.00 | Week 14, 2004 | SF | @Ari@Ari | 2 Tackles, 2 Assists |
| 39. | 4.00 | Week 11, 2004 | SF | @TB@TB | 3 Tackles, 1 Assist |
| 39. | 4.00 | Week 13, 2001 | SF | @StL@StL | 4 Tackles |
| 47. | 3.00 | Week 13, 2006 | TB | @Pit@Pit | 1 Tackle, 2 Assists |
| 47. | 3.00 | Week 03, 2005 | SF | DalDal | 2 Tackles, 1 PD |
| 47. | 3.00 | Week 04, 2004 | SF | StLStL | 3 Tackles |
| 47. | 3.00 | Week 03, 2004 | SF | @Sea@Sea | 2 Tackles, 1 Assist |