*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 42.00 | Week 11, 2008 * | NE | NYJNYJ | 400 Pass, 62 Rush, 3 TD, 1 2-Pt |
| 2. | 41.00 | Week 10, 2010 | KC | @Den@Den | 469 Pass, 3 Rush, 4 TD, 1 Fumb |
| 3. | 39.00 | Week 12, 2008 * | NE | @Mia@Mia | 415 Pass, 14 Rush, 4 TD, 1 Int |
| 4. | 35.00 | Week 05, 2011 | KC | @Ind@Ind | 257 Pass, 12 Rush, 4 TD |
| 4. | 35.00 | Week 12, 2010 | KC | @Sea@Sea | 233 Pass, 28 Rush, 4 TD |
| 6. | 32.00 | Week 15, 2013 | Min | PhiPhi | 382 Pass, 19 Rush, 3 TD, 1 Int |
| 6. | 32.00 | Week 16, 2010 | KC | TenTen | 314 Pass, 20 Rush, 3 TD |
| 6. | 32.00 | Week 16, 2008 | NE | AriAri | 345 Pass, 19 Rush, 3 TD |
| 9. | 31.00 | Week 15, 2008 | NE | @Oak@Oak | 218 Pass, 18 Rush, 4 TD, 1 Int |
| 10. | 28.00 | Week 09, 2015 | Dal | PhiPhi | 299 Pass, 17 Rush, 3 TD, 1 Int |
| 11. | 26.00 | Week 06, 2010 | KC | @Hou@Hou | 201 Pass, 8 Rush, 3 TD |
| 11. | 26.00 | Week 03, 2010 | KC | SFSF | 250 Pass, 7 Rush, 3 TD, 1 Int |
| 11. | 26.00 | Week 15, 2009 | KC | CleCle | 331 Pass, 10 Rush, 2 TD |
| 14. | 25.00 | Week 07, 2008 | NE | DenDen | 185 Pass, 1 Rush, 3 TD |
| 15. | 24.00 | Week 09, 2009 | KC | @Jac@Jac | 262 Pass, 3 Rush, 2 TD, 1 2-Pt |
| 15. | 24.00 | Week 05, 2009 | KC | DalDal | 253 Pass, 28 Rush, 2 TD |
| 17. | 23.00 | Week 02, 2012 | KC | @Buf@Buf | 301 Pass, 25 Rush, 2 TD, 1 Int, 1 Fumb |
| 18. | 22.00 | Week 14, 2013 | Min | @Bal@Bal | 265 Pass, 6 Rush, 2 TD |
| 19. | 21.00 | Week 04, 2013 | Min | PitPit | 248 Pass, 5 Rush, 2 TD |
| 20. | 20.00 | Week 11, 2009 | KC | PitPit | 248 Pass, - 1 Rush, 2 TD, 1 Fumb |
| 21. | 19.00 | Week 01, 2012 | KC | AtlAtl | 258 Pass, 20 Rush, 2 TD, 2 Int, 1 Fumb |
| 21. | 19.00 | Week 11, 2010 | KC | AriAri | 193 Pass, 2 TD |
| 21. | 19.00 | Week 09, 2010 | KC | @Oak@Oak | 216 Pass, 14 Rush, 2 TD, 1 Int |
| 21. | 19.00 | Week 07, 2010 | KC | JacJac | 193 Pass, 2 TD |
| 21. | 19.00 | Week 04, 2009 | KC | NYGNYG | 127 Pass, 25 Rush, 2 TD |
| 21. | 19.00 | Week 14, 2008 | NE | @Sea@Sea | 268 Pass, 14 Rush, 1 TD, 1 2-Pt |
| 21. | 19.00 | Week 17, 2005 | NE | MiaMia | 168 Pass, 13 Rush, 2 TD |
| 28. | 18.00 | Week 01, 2014 | Min | @STL@STL | 170 Pass, - 3 Rush, 2 TD |
| 28. | 18.00 | Week 04, 2011 | KC | MinMin | 260 Pass, 20 Rush, 1 TD |
| 30. | 17.00 | Week 03, 2011 | KC | @SD@SD | 176 Pass, 1 Rush, 2 TD, 1 Int |
| 31. | 16.00 | Week 04, 2012 | KC | SDSD | 251 Pass, 2 TD, 3 Int |
| 31. | 16.00 | Week 10, 2008 | NE | BufBuf | 234 Pass, 22 Rush, 1 TD, 1 Fumb |
| 33. | 15.00 | Week 03, 2009 | KC | @Phi@Phi | 90 Pass, - 1 Rush, 2 TD |
| 34. | 14.00 | Week 08, 2012 | KC | OakOak | 218 Pass, 35 Rush, 1 TD, 1 Int, 1 Fumb |
| 34. | 14.00 | Week 02, 2009 | KC | OakOak | |
| 34. | 14.00 | Week 08, 2008 | NE | StLStL | 267 Pass, 22 Rush, 1 TD, 2 Int |
| 37. | 13.00 | Week 13, 2013 | Min | ChiChi | 243 Pass, 1 TD, 1 Int |
| 37. | 13.00 | Week 09, 2011 | KC | MiaMia | 253 Pass, 38 Rush |
| 37. | 13.00 | Week 13, 2010 | KC | DenDen | 196 Pass, 5 Rush, 1 TD |
| 37. | 13.00 | Week 08, 2010 | KC | BufBuf | 152 Pass, 13 Rush, 1 TD |
| 37. | 13.00 | Week 01, 2008 | NE | KCKC | 152 Pass, 13 Rush, 1 TD |
| 42. | 12.00 | Week 08, 2011 | KC | SDSD | 261 Pass, 14 Rush, 1 TD, 2 Int, 1 Fumb |
| 42. | 12.00 | Week 15, 2010 | KC | @StL@StL | 184 Pass, 17 Rush, 1 TD, 1 Int |
| 42. | 12.00 | Week 12, 2009 | KC | @SD@SD | 178 Pass, 22 Rush, 1 TD, 1 Int, 1 Fumb |
| 42. | 12.00 | Week 05, 2008 | NE | @SF@SF | 259 Pass, 5 Rush, 1 TD, 2 Int |
| 46. | 11.00 | Week 17, 2013 | Min | DetDet | 189 Pass, 5 Rush, 1 TD, 1 Int |
| 46. | 11.00 | Week 06, 2013 | Min | CarCar | 241 Pass, 7 Rush, 1 TD, 2 Int |
| 46. | 11.00 | Week 16, 2009 | KC | @Cin@Cin | 180 Pass, 21 Rush, 1 TD, 2 Int |
| 49. | 10.00 | Week 05, 2017 | Ten | @Mia@Mia | 141 Pass, 1 TD, 1 Fumb |
| 49. | 10.00 | Week 17, 2016 | Ten | HouHou | 150 Pass, 2 Rush, 1 TD, 1 Int |