*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 29.00 | Week 03, 2017 | SF | LARLAR | 332 Pass, 9 Rush, 3 TD, 1 Int |
| 1. | 29.00 | Week 06, 2015 | Hou | @Jac@Jac | 293 Pass, 5 Rush, 3 TD |
| 3. | 28.00 | Week 13, 2015 | Hou | @Buf@Buf | 293 Pass, 15 Rush, 3 TD, 1 Int |
| 4. | 27.00 | Week 05, 2016 | Chi | @Ind@Ind | 397 Pass, - 1 Rush, 2 TD |
| 4. | 27.00 | Week 05, 2014 | Cle | @Ten@Ten | 292 Pass, 2 Rush, 3 TD, 1 Int |
| 6. | 26.00 | Week 05, 2017 | SF | @Ind@Ind | 353 Pass, 2 TD |
| 6. | 26.00 | Week 07, 2015 | Hou | @Mia@Mia | 273 Pass, 3 TD, 1 Int |
| 8. | 24.00 | Week 04, 2016 | Chi | DetDet | 302 Pass, - 3 Rush, 2 TD |
| 8. | 24.00 | Week 03, 2013 | Cle | @Min@Min | 321 Pass, - 2 Rush, 3 TD, 3 Int |
| 10. | 23.00 | Week 03, 2016 | Chi | @Dal@Dal | 317 Pass, - 3 Rush, 2 TD, 1 Fumb |
| 10. | 23.00 | Week 05, 2015 | Hou | IndInd | 312 Pass, 14 Rush, 2 TD, 1 Int |
| 12. | 22.32 | Week 09, 2019 | Ind | @Pit@Pit | 168 Pass, 6 Rush, 3 TD, 1 Int, 1 Fumb |
| 13. | 22.00 | Week 04, 2013 | Cle | CinCin | 269 Pass, 7 Rush, 2 TD |
| 14. | 21.00 | Week 08, 2015 | Hou | TenTen | 235 Pass, - 1 Rush, 2 TD |
| 14. | 21.00 | Week 04, 2015 | Hou | @Atl@Atl | 232 Pass, 2 TD |
| 16. | 20.00 | Week 09, 2014 | Cle | TBTB | 300 Pass, - 1 Rush, 2 TD, 2 Int |
| 17. | 18.00 | Week 12, 2015 | Hou | NONO | 205 Pass, - 3 Rush, 2 TD, 1 Int |
| 18. | 17.00 | Week 11, 2014 | Cle | HouHou | 330 Pass, - 6 Rush, 1 TD, 1 Int |
| 18. | 17.00 | Week 08, 2014 | Cle | OakOak | 275 Pass, 1 Rush, 1 TD |
| 18. | 17.00 | Week 03, 2014 | Cle | BalBal | 290 Pass, 4 Rush, 1 TD |
| 21. | 15.00 | Week 01, 2014 | Cle | @PIT@PIT | 230 Pass, - 2 Rush, 1 TD |
| 22. | 14.00 | Week 06, 2014 | Cle | PitPit | 217 Pass, 1 TD |
| 22. | 14.00 | Week 02, 2014 | Cle | NONO | 204 Pass, 1 TD |
| 24. | 13.00 | Week 17, 2015 | Hou | JacJac | 249 Pass, 1 TD, 1 Int |
| 24. | 13.00 | Week 17, 2012 | Ari | @SF@SF | 225 Pass, 6 Rush, 1 TD, 1 Int |
| 26. | 12.00 | Week 06, 2016 | Chi | JacJac | 302 Pass |
| 26. | 12.00 | Week 01, 2015 | Hou | KCKC | 236 Pass, 1 TD, 1 Int, 1 Fumb |
| 28. | 10.00 | Week 16, 2014 | Cle | @Car@Car | 134 Pass, 19 Rush, 1 TD, 1 Int |
| 28. | 10.00 | Week 17, 2010 | NE | MiaMia | 122 Pass, - 1 Rush, 1 TD |
| 30. | 9.20 | Week 10, 2021 | NE | CLECLE | 85 Pass, - 2 Rush, 1 TD |
| 31. | 8.16 | Week 10, 2019 | Ind | MiaMia | 204 Pass, 1 TD, 3 Int |
| 32. | 7.00 | Week 04, 2017 | SF | @Ari@Ari | 234 Pass, 3 Rush, 1 Int |
| 32. | 7.00 | Week 12, 2014 | Cle | @Atl@Atl | 322 Pass, 12 Rush, 3 Int |
| 32. | 7.00 | Week 10, 2014 | Cle | @Cin@Cin | 198 Pass, 1 Rush |
| 35. | 5.00 | Week 14, 2015 | Hou | NENE | 155 Pass, - 1 Rush, 1 Fumb |
| 35. | 5.00 | Week 07, 2014 | Cle | @Jac@Jac | 215 Pass, - 1 Rush, 1 Int, 1 Fumb |
| 37. | 4.00 | Week 01, 2017 | SF | CarCar | 193 Pass, - 5 Rush, 1 Int, 1 Fumb |
| 38. | 3.78 | Week 06, 2023 | LV | NENE | 102 Pass, -3 Rush |
| 39. | 3.00 | Week 04, 2020 | NE | @KC@KC | 130 Pass, 8 Rush, 1 Int, 1 Fumb |
| 39. | 3.00 | Week 02, 2016 | Chi | PhiPhi | 78 Pass |
| 39. | 3.00 | Week 10, 2015 | Hou | @Cin@Cin | 123 Pass, 15 Rush, 1 Int |
| 39. | 3.00 | Week 13, 2014 | Cle | @Buf@Buf | 192 Pass, 2 Int |
| 43. | 2.86 | Week 07, 2021 | NE | NYJNYJ | 79 Pass, - 3 Rush |
| 44. | 2.62 | Week 17, 2021 | NE | JacJac | 63 Pass, 1 Rush |
| 45. | 2.00 | Week 05, 2013 | Cle | BufBuf | 25 Pass, 11 Rush |
| 45. | 2.00 | Week 16, 2012 | Ari | ChiChi | 105 Pass, 1 Int |
| 47. | 1.48 | Week 04, 2022 | NE | @GB@GB | 37 Pass |
| 48. | 1.16 | Week 07, 2023 | LV | @Chi@Chi | 129 Pass, 2 Int |
| 49. | 1.00 | Week 10, 2017 | SF | NYGNYG | 37 Pass |
| 49. | 1.00 | Week 06, 2017 | SF | @Was@Was | 34 Pass |