*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 19.00 | Week 03, 2018 | Pit | @TB@TB | 2 Tackles, 1 Assist, 1.0 Sack, 1 Int, 1 TD, 1 PD |
| 2. | 18.00 | Week 13, 2023 | Atl | @NYJ@NYJ | 3 Tackles, 4 Assists, 2.0 Sacks, 1 FF |
| 3. | 17.00 | Week 09, 2019 | Pit | IndInd | 3 Tackles, 2.0 Sacks, 1 FF, 1 Fum Rcvy |
| 4. | 16.00 | Week 13, 2019 | Pit | CleCle | 4 Tackles, 2 Assists, 1.5 Sacks, 1 FF, 1 PD |
| 5. | 14.00 | Week 01, 2018 | Pit | @Cle@Cle | 4 Tackles, 1 Assist, 1.0 Sack, 1 FF, 2 PD |
| 5. | 14.00 | Week 17, 2016 | Pit | CleCle | 5 Tackles, 2 Assists, 1.0 Sack, 1 FF |
| 7. | 13.00 | Week 04, 2019 | Pit | CinCin | 5 Tackles, 1 Assist, 1.0 Sack, 1 FF |
| 7. | 13.00 | Week 14, 2016 | Pit | @Buf@Buf | 5 Tackles, 2.0 Sacks |
| 9. | 12.00 | Week 06, 2020 | Pit | CLECLE | 4 Tackles, 2.0 Sacks |
| 9. | 12.00 | Week 12, 2019 | Pit | @Cin@Cin | 2 Tackles, 1.0 Sack, 1 FF, 1 Fum Rcvy |
| 11. | 11.00 | Week 08, 2020 | Pit | @BAL@BAL | 4 Tackles, 1.0 Sack, 1 FF |
| 11. | 11.00 | Week 16, 2019 | Pit | @NYJ@NYJ | 2 Tackles, 5 Assists, 1.0 Sack |
| 13. | 10.00 | Week 06, 2023 | Atl | WasWas | 1 Tackle, 3 Assists, 1.5 Sacks |
| 13. | 10.00 | Week 05, 2019 | Pit | BalBal | 4 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| 15. | 9.00 | Week 13, 2022 | Ten | @Phi@Phi | 2 Tackles, 1.0 Sack, 1 FF |
| 15. | 9.00 | Week 02, 2020 | Pit | DenDen | 1 Tackle, 1 Assist, 1.0 Sack, 1 FF |
| 15. | 9.00 | Week 14, 2019 | Pit | @Ari@Ari | 4 Tackles, 1 Assist, 1.0 Sack |
| 15. | 9.00 | Week 08, 2019 | Pit | MiaMia | 3 Tackles, 2 Assists, 1.0 Sack |
| 15. | 9.00 | Week 14, 2018 | Pit | @Oak@Oak | 2 Tackles, 3 Assists, 1.0 Sack |
| 15. | 9.00 | Week 16, 2016 | Pit | BalBal | 3 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| 21. | 8.00 | Week 18, 2023 | Atl | @NO@NO | 1 Tackle, 1.0 Sack, 1 FF |
| 21. | 8.00 | Week 01, 2022 | Ten | NYGNYG | 1 Tackle, 1.0 Sack, 1 Fum Rcvy |
| 21. | 8.00 | Week 16, 2021 | Ten | SFSF | 3 Tackles, 1 Assist, 1.0 Sack |
| 21. | 8.00 | Week 07, 2021 | Ten | KCKC | 1 Tackle, 1.0 Sack, 1 FF |
| 21. | 8.00 | Week 11, 2020 | Pit | @Jac@Jac | 2 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| 21. | 8.00 | Week 03, 2020 | Pit | HouHou | 1 Tackle, 1 Assist, 1.5 Sacks |
| 21. | 8.00 | Week 17, 2019 | Pit | @Bal@Bal | 4 Tackles, 1.0 Sack |
| 21. | 8.00 | Week 01, 2019 | Pit | @NE@NE | 4 Tackles, 1.0 Sack |
| 21. | 8.00 | Week 10, 2017 | Pit | @Ind@Ind | 4 Tackles, 1.0 Sack |
| 21. | 8.00 | Week 02, 2015 | Pit | SFSF | 3 Tackles, 1 Assist, 1.0 Sack |
| 31. | 7.00 | Week 08, 2023 | Atl | @Ten@Ten | 2 Tackles, 1 Assist, 1.0 Sack |
| 31. | 7.00 | Week 07, 2022 | Ten | IndInd | 2 Tackles, 1 Assist, 1.0 Sack |
| 31. | 7.00 | Week 10, 2020 | Pit | CINCIN | 2 Tackles, 1 Assist, 1.0 Sack |
| 31. | 7.00 | Week 07, 2017 | Pit | CinCin | 1 Tackle, 2 Assists, 1.0 Sack |
| 31. | 7.00 | Week 02, 2017 | Pit | MinMin | 1 Tackle, 1 Assist, 1.0 Sack, 1 PD |
| 36. | 6.00 | Week 04, 2023 | Atl | @Jac@Jac | 4 Assists, 0.5 Sack |
| 36. | 6.00 | Week 14, 2022 | Ten | JacJac | 5 Tackles, 1 Assist |
| 36. | 6.00 | Week 08, 2022 | Ten | @Hou@Hou | 2 Tackles, 1.0 Sack |
| 36. | 6.00 | Week 15, 2021 | Ten | @PIT@PIT | 1 Tackle, 1 Assist, 1.0 Sack |
| 36. | 6.00 | Week 10, 2018 | Pit | CarCar | 2 Tackles, 1.0 Sack |
| 36. | 6.00 | Week 05, 2018 | Pit | AtlAtl | 3 Tackles, 3 Assists |
| 36. | 6.00 | Week 16, 2017 | Pit | @Hou@Hou | 5 Tackles, 1 Assist |
| 36. | 6.00 | Week 15, 2017 | Pit | NENE | 2 Tackles, 1.0 Sack |
| 36. | 6.00 | Week 13, 2017 | Pit | @Cin@Cin | 1 Tackle, 1 Assist, 1.0 Sack |
| 36. | 6.00 | Week 04, 2017 | Pit | @Bal@Bal | 3 Tackles, 1 Assist, 0.5 Sack |
| 36. | 6.00 | Week 05, 2015 | Pit | @SD@SD | 2 Tackles, 1.0 Sack |
| 36. | 6.00 | Week 01, 2015 | Pit | @NE@NE | 2 Tackles, 1.0 Sack |
| 48. | 5.00 | Week 17, 2023 | Atl | @Chi@Chi | 1 Tackle, 2 Assists, 0.5 Sack |
| 48. | 5.00 | Week 16, 2023 | Atl | IndInd | |
| 48. | 5.00 | Week 12, 2020 | Pit | BALBAL | 5 Tackles |