*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 15.00 | Week 12, 2022 | LV | @Sea@Sea | 4 Tackles, 5 Assists, 1 Int, 1 PD |
| 1. | 15.00 | Week 16, 2015 | SD | @Oak@Oak | 10 Tackles, 1 Assist, 1.0 Sack |
| 3. | 14.00 | Week 11, 2021 | LV | CINCIN | 9 Tackles, 3 Assists, 2 PD |
| 3. | 14.00 | Week 06, 2021 | LV | @DEN@DEN | 6 Tackles, 5 Assists, 1 Fum Rcvy |
| 3. | 14.00 | Week 03, 2021 | LV | MIAMIA | 10 Tackles, 4 Assists |
| 3. | 14.00 | Week 07, 2018 | LAC | TenTen | 6 Tackles, 2 Assists, 1 Int, 1 PD |
| 3. | 14.00 | Week 03, 2016 | SD | @Ind@Ind | 8 Tackles, 2 Assists, 1.0 Sack |
| 8. | 13.00 | Week 01, 2021 | LV | BALBAL | 5 Tackles, 5 Assists, 1 Fum Rcvy |
| 8. | 13.00 | Week 07, 2016 | SD | @Atl@Atl | 6 Tackles, 1 Assist, 1 Int, 1 PD |
| 10. | 12.00 | Week 05, 2022 | LV | @KC@KC | 6 Tackles, 2 Assists, 1.0 Sack |
| 10. | 12.00 | Week 13, 2021 | LV | WASWAS | 9 Tackles, 3 Assists |
| 10. | 12.00 | Week 05, 2021 | LV | CHICHI | 10 Tackles, 2 Assists |
| 10. | 12.00 | Week 04, 2021 | LV | @LAC@LAC | 8 Tackles, 4 Assists |
| 10. | 12.00 | Week 02, 2021 | LV | @PIT@PIT | 6 Tackles, 6 Assists |
| 15. | 11.00 | Week 08, 2023 | Hou | @Car@Car | 6 Tackles, 3 Assists, 0.5 Sack |
| 15. | 11.00 | Week 01, 2023 | Hou | @Bal@Bal | |
| 15. | 11.00 | Week 10, 2021 | LV | KCKC | 7 Tackles, 4 Assists |
| 15. | 11.00 | Week 09, 2021 | LV | @NYG@NYG | 7 Tackles, 3 Assists, 1 PD |
| 15. | 11.00 | Week 16, 2016 | SD | @Cle@Cle | 5 Tackles, 2 Assists, 1.0 Sack |
| 15. | 11.00 | Week 06, 2015 | SD | @GB@GB | 7 Tackles, 1 Assist, 1 FF |
| 21. | 10.00 | Week 15, 2023 | Hou | @Ten@Ten | 7 Tackles, 3 Assists |
| 21. | 10.00 | Week 16, 2022 | LV | @Pit@Pit | 2 Tackles, 2 Assists, 1 Int, 1 PD |
| 21. | 10.00 | Week 09, 2022 | LV | @Jac@Jac | 6 Tackles, 4 Assists |
| 21. | 10.00 | Week 17, 2021 | LV | @IND@IND | 5 Tackles, 2 Assists, 1 FF |
| 21. | 10.00 | Week 13, 2019 | LAC | @Den@Den | 3 Tackles, 1 Assist, 1 Int, 1 PD |
| 21. | 10.00 | Week 11, 2019 | LAC | KCKC | 6 Tackles, 1 Assist, 1 FF |
| 21. | 10.00 | Week 03, 2018 | LAC | @LAR@LAR | 6 Tackles, 4 Assists |
| 21. | 10.00 | Week 12, 2016 | SD | @Hou@Hou | 6 Tackles, 4 Assists |
| 21. | 10.00 | Week 13, 2015 | SD | DenDen | 10 Tackles |
| 21. | 10.00 | Week 11, 2015 | SD | KCKC | 3 Tackles, 3 Assists, 1.0 Sack |
| 31. | 9.00 | Week 15, 2022 | LV | NENE | 8 Tackles, 1 Assist |
| 31. | 9.00 | Week 18, 2021 | LV | LACLAC | 8 Tackles, 1 Assist |
| 31. | 9.00 | Week 14, 2017 | LAC | WasWas | 5 Tackles, 4 Assists |
| 31. | 9.00 | Week 10, 2017 | LAC | @Jac@Jac | 8 Tackles, 1 Assist |
| 31. | 9.00 | Week 13, 2016 | SD | TBTB | 9 Tackles |
| 36. | 8.00 | Week 02, 2023 | Hou | IndInd | 5 Tackles, 3 Assists |
| 36. | 8.00 | Week 08, 2022 | LV | @NO@NO | 6 Tackles, 2 Assists |
| 36. | 8.00 | Week 07, 2021 | LV | PHIPHI | 6 Tackles, 2 Assists |
| 36. | 8.00 | Week 07, 2019 | LAC | @Ten@Ten | 6 Tackles, 2 Assists |
| 36. | 8.00 | Week 06, 2018 | LAC | @Cle@Cle | 2 Tackles, 6 Assists |
| 41. | 7.00 | Week 16, 2023 | Hou | CleCle | |
| 41. | 7.00 | Week 14, 2022 | LV | @LAR@LAR | 3 Tackles, 4 Assists |
| 41. | 7.00 | Week 13, 2022 | LV | LACLAC | 2 Tackles, 5 Assists |
| 41. | 7.00 | Week 12, 2021 | LV | @DAL@DAL | 2 Tackles, 5 Assists |
| 41. | 7.00 | Week 17, 2020 | LAC | @KC@KC | 5 Tackles, 2 Assists |
| 41. | 7.00 | Week 16, 2020 | LAC | DENDEN | 5 Tackles, 2 Assists |
| 41. | 7.00 | Week 11, 2020 | LAC | NYJNYJ | 2 Tackles, 1 Assist, 1.0 Sack |
| 41. | 7.00 | Week 04, 2020 | LAC | @TB@TB | 2 Tackles, 4 Assists, 1 PD |
| 41. | 7.00 | Week 08, 2019 | LAC | @Chi@Chi | 5 Tackles, 2 Assists |
| 41. | 7.00 | Week 05, 2018 | LAC | OakOak | 4 Tackles, 3 Assists |