*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 14.00 | Week 17, 2018 | Buf | MiaMia | 2 Tackles, 2.0 Sacks, 1 FF, 1 PD |
| 2. | 13.00 | Week 13, 2020 | Mia | CINCIN | 3 Tackles, 1 Assist, 2.0 Sacks, 1 PD |
| 3. | 12.00 | Week 09, 2020 | Mia | @ARI@ARI | 2 Tackles, 1 Assist, 1 Fum Rcvy |
| 4. | 11.00 | Week 11, 2017 | Buf | @LAC@LAC | 4 Tackles, 1.0 Sack, 1 FF |
| 5. | 10.00 | Week 15, 2022 | Buf | MiaMia | 1 Tackle, 1 Assist, 1.0 Sack, 1 FF, 1 PD |
| 5. | 10.00 | Week 08, 2020 | Mia | LARLAR | 1 Tackle, 2 Assists, 1.0 Sack, 1 FF |
| 5. | 10.00 | Week 15, 2019 | Buf | @Pit@Pit | 3 Tackles, 1.0 Sack, 1 FF |
| 5. | 10.00 | Week 12, 2019 | Buf | DenDen | 2 Tackles, 2.0 Sacks |
| 9. | 9.00 | Week 01, 2019 | Buf | @NYJ@NYJ | 1 Tackle, 3 Assists, 1.0 Sack, 1 PD |
| 9. | 9.00 | Week 02, 2017 | Buf | @Car@Car | 2 Tackles, 3 Assists, 1.0 Sack |
| 11. | 8.00 | Week 10, 2018 | Buf | @NYJ@NYJ | 2 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| 11. | 8.00 | Week 09, 2018 | Buf | ChiChi | 4 Tackles, 3 Assists, 1 PD |
| 13. | 7.00 | Week 08, 2021 | NYJ | CINCIN | 1 Int, 2 PD |
| 13. | 7.00 | Week 13, 2019 | Buf | @Dal@Dal | 4 Tackles, 1 Assist, 0.5 Sack |
| 13. | 7.00 | Week 08, 2019 | Buf | PhiPhi | 2 Tackles, 1 Assist, 1.0 Sack |
| 13. | 7.00 | Week 08, 2016 | Buf | NENE | 1 Tackle, 2 Assists, 1.0 Sack |
| 17. | 6.00 | Week 14, 2022 | Buf | NYJNYJ | 2 Tackles, 1.0 Sack |
| 17. | 6.00 | Week 06, 2022 | Buf | @KC@KC | 2 Tackles, 1.0 Sack |
| 17. | 6.00 | Week 05, 2021 | NYJ | @ATL@ATL | 3 Tackles, 1 Fum Rcvy |
| 17. | 6.00 | Week 04, 2020 | Mia | SEASEA | 1 Tackle, 1 Assist, 1.0 Sack |
| 17. | 6.00 | Week 11, 2019 | Buf | @Mia@Mia | 2 Tackles, 1.0 Sack |
| 17. | 6.00 | Week 06, 2018 | Buf | @Hou@Hou | 2 Tackles, 1.0 Sack |
| 17. | 6.00 | Week 13, 2017 | Buf | NENE | 1 Tackle, 1 Assist, 1.0 Sack |
| 24. | 5.00 | Week 11, 2023 | Buf | NYJNYJ | 1 Tackle, 1.0 Sack |
| 24. | 5.00 | Week 10, 2022 | Buf | MinMin | 1 Tackle, 2 Assists, 0.5 Sack |
| 24. | 5.00 | Week 14, 2021 | NYJ | NONO | 2 Tackles, 1 Assist, 0.5 Sack |
| 24. | 5.00 | Week 10, 2021 | NYJ | BUFBUF | 1 Tackle, 2 Assists, 0.5 Sack |
| 24. | 5.00 | Week 10, 2020 | Mia | LACLAC | 2 Tackles, 3 Assists |
| 24. | 5.00 | Week 10, 2017 | Buf | NONO | 3 Tackles, 1 Assist, 1 PD |
| 24. | 5.00 | Week 03, 2017 | Buf | DenDen | 1 Tackle, 1.0 Sack |
| 24. | 5.00 | Week 09, 2016 | Buf | @Sea@Sea | 1 Tackle, 1.0 Sack |
| 32. | 4.00 | Week 16, 2022 | Buf | @Chi@Chi | 4 Tackles |
| 32. | 4.00 | Week 02, 2021 | NYJ | NENE | 2 Tackles, 2 Assists |
| 32. | 4.00 | Week 14, 2020 | Mia | KCKC | 3 Tackles, 1 Assist |
| 32. | 4.00 | Week 15, 2018 | Buf | DetDet | 1 Tackle, 2 Assists, 1 PD |
| 32. | 4.00 | Week 14, 2018 | Buf | NYJNYJ | 1 Tackle, 1 Assist, 2 PD |
| 32. | 4.00 | Week 05, 2018 | Buf | TenTen | 1 Tackle, 1 FF |
| 32. | 4.00 | Week 12, 2017 | Buf | @KC@KC | 2 Tackles, 2 Assists |
| 32. | 4.00 | Week 07, 2017 | Buf | TBTB | 1 Tackle, 3 Assists |
| 32. | 4.00 | Week 01, 2017 | Buf | NYJNYJ | 2 Tackles, 1 Assist, 1 PD |
| 32. | 4.00 | Week 15, 2016 | Buf | CleCle | 1 Tackle, 1 FF |
| 32. | 4.00 | Week 13, 2016 | Buf | @Oak@Oak | 1 Tackle, 2 Assists, 1 PD |
| 43. | 3.00 | Week 18, 2022 | Buf | NENE | 1 Tackle, 2 Assists |
| 43. | 3.00 | Week 13, 2022 | Buf | @NE@NE | 3 Tackles |
| 43. | 3.00 | Week 09, 2022 | Buf | @NYJ@NYJ | 1 Tackle, 2 Assists |
| 43. | 3.00 | Week 01, 2021 | NYJ | @CAR@CAR | 3 Tackles |
| 43. | 3.00 | Week 03, 2020 | Mia | @Jac@Jac | 1 Tackle, 2 Assists |
| 43. | 3.00 | Week 01, 2020 | Mia | @NE@NE | 1 Tackle, 2 Assists |
| 43. | 3.00 | Week 14, 2019 | Buf | BalBal | 2 Assists, 1 PD |
| 43. | 3.00 | Week 10, 2019 | Buf | @Cle@Cle | 1 Tackle, 2 Assists |