*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 25.00 | Week 03, 2021 | Cle | CHICHI | 6 Tackles, 1 Assist, 4.5 Sacks |
| 2. | 24.00 | Week 07, 2023 | Cle | @Ind@Ind | 7 Tackles, 2 Assists, 2.0 Sacks, 2 FF, 1 PD |
| 3. | 22.00 | Week 03, 2023 | Cle | TenTen | 4 Tackles, 1 Assist, 3.5 Sacks, 1 FF |
| 4. | 21.00 | Week 01, 2018 | Cle | PitPit | 5 Tackles, 1 Assist, 2.0 Sacks, 2 FF, 1 PD |
| 5. | 19.00 | Week 14, 2021 | Cle | BALBAL | 3 Tackles, 1.0 Sack, 1 TD, 1 FF, 1 Fum Rcvy |
| 6. | 18.00 | Week 03, 2020 | Cle | WasWas | 4 Tackles, 2.0 Sacks, 1 FF, 1 Fum Rcvy |
| 7. | 17.00 | Week 02, 2019 | Cle | @NYJ@NYJ | |
| 8. | 16.00 | Week 14, 2022 | Cle | @Cin@Cin | 4 Tackles, 2 Assists, 2.0 Sacks, 2 PD |
| 8. | 16.00 | Week 06, 2022 | Cle | NENE | 3 Tackles, 2 Assists, 2.0 Sacks, 1 FF |
| 8. | 16.00 | Week 01, 2022 | Cle | @CAR@CAR | 4 Tackles, 2.0 Sacks, 1 FF, 1 PD |
| 11. | 14.00 | Week 17, 2022 | Cle | @Was@Was | 4 Tackles, 4 Assists, 1.5 Sacks |
| 11. | 14.00 | Week 04, 2020 | Cle | @DAL@DAL | 2 Tackles, 1 Assist, 2.0 Sacks, 1 FF |
| 13. | 13.00 | Week 06, 2019 | Cle | SeaSea | 3 Tackles, 2 Assists, 2.0 Sacks |
| 13. | 13.00 | Week 01, 2019 | Cle | TenTen | 4 Tackles, 1 Assist, 2.0 Sacks |
| 13. | 13.00 | Week 07, 2018 | Cle | @TB@TB | 2 Tackles, 2.0 Sacks, 1 FF |
| 16. | 12.00 | Week 03, 2018 | Cle | NYJNYJ | 3 Tackles, 2.0 Sacks, 1 PD |
| 17. | 11.00 | Week 18, 2022 | Cle | @Pit@Pit | 3 Tackles, 4 Assists, 1.0 Sack |
| 17. | 11.00 | Week 07, 2020 | Cle | @CIN@CIN | 3 Tackles, 2.0 Sacks |
| 17. | 11.00 | Week 04, 2018 | Cle | @Oak@Oak | 7 Tackles, 2 Assists, 0.5 Sack |
| 20. | 10.00 | Week 11, 2023 | Cle | PitPit | 2 Tackles, 2.0 Sacks |
| 20. | 10.00 | Week 12, 2021 | Cle | @BAL@BAL | 3 Tackles, 2 Assists, 1.0 Sack, 1 PD |
| 20. | 10.00 | Week 02, 2020 | Cle | CinCin | 3 Tackles, 1.0 Sack, 1 FF |
| 20. | 10.00 | Week 17, 2017 | Cle | @Pit@Pit | 3 Tackles, 1.0 Sack, 1 FF |
| 20. | 10.00 | Week 05, 2017 | Cle | NYJNYJ | 2 Tackles, 2.0 Sacks |
| 25. | 9.00 | Week 10, 2023 | Cle | @Bal@Bal | 1 Tackle, 2 Assists, 1.5 Sacks |
| 25. | 9.00 | Week 09, 2023 | Cle | AriAri | 1 Tackle, 1.0 Sack, 1 Fum Rcvy, 1 PD |
| 25. | 9.00 | Week 08, 2023 | Cle | @Sea@Sea | 2 Tackles, 1.0 Sack, 1 FF |
| 25. | 9.00 | Week 15, 2022 | Cle | BalBal | 2 Tackles, 1 Assist, 1.5 Sacks |
| 25. | 9.00 | Week 12, 2022 | Cle | TBTB | 1 Tackle, 2 Assists, 1.5 Sacks |
| 25. | 9.00 | Week 08, 2022 | Cle | CinCin | 1 Tackle, 1 Assist, 1.5 Sacks, 1 PD |
| 25. | 9.00 | Week 07, 2021 | Cle | DENDEN | 1 Tackle, 2 Assists, 1.5 Sacks |
| 25. | 9.00 | Week 16, 2020 | Cle | @NYJ@NYJ | 2 Tackles, 2 Assists, 1.0 Sack, 1 PD |
| 25. | 9.00 | Week 03, 2019 | Cle | LARLAR | 1 Tackle, 1 Assist, 1.0 Sack, 1 FF |
| 25. | 9.00 | Week 14, 2018 | Cle | CarCar | 4 Tackles, 1 Assist, 1.0 Sack |
| 25. | 9.00 | Week 13, 2018 | Cle | @Hou@Hou | 2 Tackles, 1 Assist, 1.5 Sacks |
| 25. | 9.00 | Week 06, 2017 | Cle | @Hou@Hou | 2 Tackles, 3 Assists, 1.0 Sack |
| 37. | 8.00 | Week 07, 2022 | Cle | @Bal@Bal | 4 Tackles, 1.0 Sack |
| 37. | 8.00 | Week 09, 2021 | Cle | @CIN@CIN | 1 Tackle, 1 Assist, 1.5 Sacks |
| 37. | 8.00 | Week 08, 2021 | Cle | PITPIT | 4 Tackles, 1.0 Sack |
| 37. | 8.00 | Week 01, 2021 | Cle | @KC@KC | 3 Tackles, 1 Assist, 1.0 Sack |
| 37. | 8.00 | Week 10, 2020 | Cle | HOUHOU | 4 Tackles, 2 Assists, 0.5 Sack |
| 37. | 8.00 | Week 06, 2020 | Cle | @PIT@PIT | 3 Tackles, 1 Assist, 1.0 Sack |
| 37. | 8.00 | Week 05, 2020 | Cle | INDIND | 3 Tackles, 1 Assist, 1.0 Sack |
| 37. | 8.00 | Week 08, 2019 | Cle | @NE@NE | 3 Tackles, 1 Assist, 1.0 Sack |
| 37. | 8.00 | Week 07, 2017 | Cle | TenTen | 3 Tackles, 1 Assist, 1.0 Sack |
| 46. | 7.00 | Week 17, 2023 | Cle | NYJNYJ | 3 Tackles, 1.0 Sack |
| 46. | 7.00 | Week 11, 2022 | Cle | @Buf@Buf | 2 Tackles, 1 Assist, 1.0 Sack |
| 46. | 7.00 | Week 06, 2021 | Cle | ARIARI | 2 Tackles, 1 Assist, 1.0 Sack |
| 46. | 7.00 | Week 05, 2021 | Cle | @LAC@LAC | 2 Tackles, 1.0 Sack, 1 PD |
| 46. | 7.00 | Week 04, 2021 | Cle | @MIN@MIN | 3 Tackles, 2 Assists, 0.5 Sack |