*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 27.00 | Week 01, 2023 * | Pit | SFSF | 5 Tackles, 3.0 Sacks, 2 FF, 1 Fum Rcvy, 1 PD |
| 2. | 23.00 | Week 17, 2021 | Pit | CLECLE | 5 Tackles, 4.0 Sacks, 2 PD |
| 2. | 23.00 | Week 13, 2021 | Pit | BALBAL | 5 Tackles, 1 Assist, 3.5 Sacks, 1 FF |
| 2. | 23.00 | Week 05, 2018 | Pit | AtlAtl | 6 Tackles, 2 Assists, 3.0 Sacks, 1 FF |
| 5. | 22.00 | Week 01, 2018 | Pit | @Cle@Cle | 7 Tackles, 3 Assists, 3.0 Sacks |
| 6. | 21.00 | Week 06, 2021 * | Pit | SEASEA | 6 Tackles, 1 Assist, 2.0 Sacks, 1 FF, 3 PD |
| 7. | 20.00 | Week 09, 2021 | Pit | CHICHI | 4 Tackles, 3 Assists, 3.0 Sacks, 1 PD |
| 7. | 20.00 | Week 08, 2019 | Pit | MiaMia | 3 Tackles, 2.0 Sacks, 2 FF, 1 Fum Rcvy |
| 7. | 20.00 | Week 11, 2018 | Pit | @Jac@Jac | 6 Tackles, 2.0 Sacks, 2 FF |
| 7. | 20.00 | Week 01, 2017 | Pit | @Cle@Cle | 5 Tackles, 1 Assist, 2.0 Sacks, 1 Int, 1 PD |
| 11. | 18.00 | Week 02, 2023 | Pit | CleCle | 2 Tackles, 2 Assists, 1.0 Sack, 1 TD, 1 Fum Rcvy, 1 PD |
| 12. | 17.00 | Week 01, 2022 | Pit | @CIN@CIN | 6 Tackles, 1.0 Sack, 1 Int, 2 PD |
| 12. | 17.00 | Week 17, 2018 | Pit | CinCin | 4 Tackles, 3 Assists, 1.0 Sack, 2 FF |
| 14. | 16.00 | Week 18, 2023 | Pit | @Bal@Bal | 6 Tackles, 2 Assists, 2.0 Sacks |
| 14. | 16.00 | Week 12, 2023 | Pit | @Cin@Cin | 5 Tackles, 2.0 Sacks, 1 FF |
| 14. | 16.00 | Week 10, 2019 | Pit | LARLAR | 4 Tackles, 1 Assist, 2.0 Sacks, 1 FF |
| 17. | 15.00 | Week 05, 2023 | Pit | BalBal | 2 Tackles, 2.0 Sacks, 1 Fum Rcvy, 2 PD |
| 17. | 15.00 | Week 11, 2022 | Pit | CinCin | 2 Tackles, 4 Assists, 0.5 Sack, 1 Int, 2 PD |
| 17. | 15.00 | Week 08, 2021 | Pit | @CLE@CLE | 4 Tackles, 2 Assists, 1.5 Sacks, 1 Fum Rcvy |
| 17. | 15.00 | Week 04, 2021 | Pit | @GB@GB | 3 Tackles, 1 Assist, 2.0 Sacks, 1 Fum Rcvy |
| 17. | 15.00 | Week 12, 2020 | Pit | BALBAL | 4 Tackles, 3 Assists, 2.0 Sacks |
| 17. | 15.00 | Week 16, 2019 | Pit | @NYJ@NYJ | 2 Tackles, 3 Assists, 1.0 Sack, 1 FF, 1 Fum Rcvy |
| 23. | 14.00 | Week 15, 2021 | Pit | TENTEN | 4 Tackles, 1 Assist, 1.5 Sacks, 1 Fum Rcvy |
| 23. | 14.00 | Week 01, 2021 | Pit | @BUF@BUF | 3 Tackles, 2.0 Sacks, 1 FF |
| 23. | 14.00 | Week 16, 2020 | Pit | INDIND | 3 Tackles, 2.0 Sacks, 1 FF |
| 23. | 14.00 | Week 02, 2020 | Pit | DenDen | 3 Tackles, 1 Assist, 2.5 Sacks |
| 27. | 13.00 | Week 13, 2020 | Pit | WASWAS | 5 Tackles, 1 Assist, 1.0 Sack, 1 FF |
| 27. | 13.00 | Week 02, 2019 | Pit | SeaSea | |
| 27. | 13.00 | Week 17, 2017 | Pit | CleCle | 6 Tackles, 2 Assists, 1.0 Sack, 1 PD |
| 30. | 12.00 | Week 10, 2023 | Pit | GBGB | 7 Tackles, 1 Assist, 1.0 Sack |
| 30. | 12.00 | Week 10, 2020 | Pit | CINCIN | 4 Tackles, 2.0 Sacks |
| 30. | 12.00 | Week 03, 2019 | Pit | @SF@SF | 2 Tackles, 1 Int, 1 Fum Rcvy, 2 PD |
| 33. | 11.00 | Week 16, 2023 | Pit | CinCin | |
| 33. | 11.00 | Week 15, 2023 | Pit | @Ind@Ind | 2 Tackles, 1 Assist, 2.0 Sacks |
| 33. | 11.00 | Week 02, 2021 | Pit | LVLV | 3 Tackles, 1 Assist, 1.0 Sack, 1 FF |
| 33. | 11.00 | Week 04, 2019 | Pit | CinCin | 1 Tackle, 1 Assist, 1.5 Sacks, 1 Fum Rcvy |
| 33. | 11.00 | Week 08, 2018 | Pit | CleCle | 6 Tackles, 1 Assist, 1.0 Sack |
| 33. | 11.00 | Week 14, 2017 | Pit | BalBal | 4 Tackles, 1.0 Sack, 1 FF |
| 39. | 10.00 | Week 11, 2023 | Pit | @Cle@Cle | 4 Tackles, 2 Assists, 1.0 Sack |
| 39. | 10.00 | Week 03, 2023 | Pit | @LV@LV | 2 Tackles, 2.0 Sacks |
| 39. | 10.00 | Week 18, 2021 | Pit | @BAL@BAL | 3 Tackles, 2 Assists, 1.0 Sack, 1 PD |
| 39. | 10.00 | Week 07, 2020 | Pit | @TEN@TEN | 4 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| 39. | 10.00 | Week 17, 2019 | Pit | @Bal@Bal | 4 Tackles, 1 Assist, 0.5 Sack, 1 FF |
| 39. | 10.00 | Week 15, 2019 | Pit | BufBuf | 3 Tackles, 1 Assist, 0.5 Sack, 1 FF, 1 PD |
| 39. | 10.00 | Week 12, 2019 | Pit | @Cin@Cin | 2 Tackles, 1.0 Sack, 1 FF, 1 PD |
| 39. | 10.00 | Week 07, 2017 | Pit | CinCin | 5 Tackles, 1 Assist, 1.0 Sack |
| 39. | 10.00 | Week 05, 2017 | Pit | JacJac | 5 Tackles, 1 Assist, 1.0 Sack |
| 48. | 9.00 | Week 13, 2023 | Pit | AriAri | 3 Tackles, 3 Assists, 0.5 Sack, 1 PD |
| 48. | 9.00 | Week 14, 2022 | Pit | BalBal | 3 Tackles, 2 Assists, 1.0 Sack |
| 48. | 9.00 | Week 10, 2021 | Pit | DETDET | 3 Tackles, 2 Assists, 1.0 Sack |