*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 26.70 | Week 10, 2018 | SF | NYGNYG | 101 Rush, 31 Receiving, 3 Rec, 2 TD |
| 2. | 26.40 | Week 05, 2019 | SF | CleCle | 114 Rush, 15 Receiving, 3 Rec, 2 TD |
| 3. | 23.40 | Week 02, 2018 | SF | DetDet | 138 Rush, 21 Receiving, 3 Rec, 1 TD |
| 4. | 17.50 | Week 10, 2021 | Buf | @NYJ@NYJ | 28 Rush, 22 Receiving, 3 Rec, 2 TD, 1 Fumb |
| 5. | 15.50 | Week 12, 2018 | SF | @TB@TB | 106 Rush, 34 Receiving, 3 Rec |
| 6. | 14.00 | Week 16, 2017 | SF | JacJac | 74 Rush, 8 Receiving, 1 TD |
| 7. | 13.70 | Week 02, 2019 | SF | @Cin@Cin | |
| 8. | 13.20 | Week 03, 2018 | SF | @KC@KC | 90 Rush, 27 Receiving, 3 Rec |
| 9. | 12.60 | Week 05, 2018 | SF | AriAri | 56 Rush, 5 Receiving, 1 Rec, 1 TD |
| 10. | 12.50 | Week 12, 2021 | Buf | @NO@NO | 26 Rush, 29 Receiving, 2 Rec, 1 TD |
| 11. | 12.10 | Week 15, 2018 | SF | SeaSea | 50 Rush, 46 Receiving, 5 Rec |
| 11. | 12.10 | Week 06, 2018 | SF | @GB@GB | 61 Rush, 1 TD |
| 13. | 11.00 | Week 10, 2017 | SF | NYGNYG | 55 Rush, 3 Receiving, 1 TD |
| 13. | 11.00 | Week 08, 2017 | SF | @Phi@Phi | 17 Rush, 39 Receiving, 1 TD |
| 15. | 10.30 | Week 04, 2023 | NYG | SeaSea | 30 Rush, 48 Receiving, 5 Rec |
| 16. | 10.20 | Week 09, 2019 | SF | @Ari@Ari | 78 Rush, 14 Receiving, 2 Rec |
| 17. | 10.00 | Week 17, 2017 | SF | @LAR@LAR | 72 Rush, 32 Receiving |
| 18. | 9.80 | Week 03, 2019 | SF | PitPit | 68 Rush, 20 Receiving, 2 Rec |
| 19. | 9.40 | Week 11, 2022 | NYG | DetDet | 13 Rush, 16 Receiving, 1 Rec, 1 TD |
| 20. | 9.30 | Week 03, 2023 | NYG | @SF@SF | 17 Rush, 1 Receiving, 3 Rec, 1 TD |
| 21. | 8.60 | Week 15, 2020 | Mia | NENE | 86 Rush |
| 21. | 8.60 | Week 04, 2018 | SF | @LAC@LAC | 39 Rush, 32 Receiving, 3 Rec |
| 23. | 8.30 | Week 06, 2019 | SF | @LAR@LAR | 36 Rush, 27 Receiving, 4 Rec |
| 24. | 7.50 | Week 18, 2022 | NYG | @Phi@Phi | 28 Rush, 12 Receiving, 7 Rec |
| 25. | 7.20 | Week 17, 2022 | NYG | IndInd | 59 Rush, 8 Receiving, 1 Rec |
| 25. | 7.20 | Week 11, 2021 | Buf | INDIND | 51 Rush, 16 Receiving, 1 Rec |
| 25. | 7.20 | Week 13, 2018 | SF | @Sea@Sea | 6 Rush, 51 Receiving, 3 Rec |
| 28. | 7.00 | Week 05, 2017 | SF | @Ind@Ind | 49 Rush, 22 Receiving |
| 29. | 6.40 | Week 05, 2020 | Mia | @SF@SF | 28 Rush, 31 Receiving, 1 Rec |
| 30. | 6.30 | Week 04, 2020 | Mia | SEASEA | 9 Rush, 39 Receiving, 3 Rec |
| 30. | 6.30 | Week 14, 2019 | SF | @NO@NO | 54 Rush, 4 Receiving, 1 Rec |
| 32. | 5.60 | Week 01, 2018 | SF | @Min@Min | 46 Rush, 5 Receiving, 1 Rec |
| 33. | 5.50 | Week 08, 2019 | SF | CarCar | 35 Rush, 15 Receiving, 1 Rec |
| 34. | 5.30 | Week 12, 2020 | Mia | @NYJ@NYJ | |
| 35. | 5.20 | Week 09, 2018 | SF | OakOak | 44 Rush, 3 Receiving, 1 Rec |
| 36. | 4.40 | Week 02, 2020 | Mia | BufBuf | 37 Rush, 2 Receiving, 1 Rec |
| 37. | 4.20 | Week 08, 2018 | SF | @Ari@Ari | 42 Rush |
| 38. | 4.10 | Week 07, 2019 | SF | @Was@Was | 35 Rush, 1 Receiving, 1 Rec |
| 39. | 4.00 | Week 13, 2017 | SF | @Chi@Chi | 45 Rush, 4 Receiving |
| 40. | 3.80 | Week 07, 2022 | NYG | @Jac@Jac | 19 Rush, 14 Receiving, 1 Rec |
| 41. | 3.70 | Week 05, 2022 | NYG | @GB@GB | 14 Rush, 13 Receiving, 2 Rec |
| 41. | 3.70 | Week 01, 2019 | SF | @TB@TB | 37 Rush |
| 43. | 3.50 | Week 10, 2019 | SF | SeaSea | 18 Rush, 7 Receiving, 2 Rec |
| 44. | 3.20 | Week 06, 2020 | Mia | NYJNYJ | 15 Rush, 7 Receiving, 2 Rec |
| 45. | 3.10 | Week 15, 2023 | NYG | @NO@NO | 10 Rush, 11 Receiving, 2 Rec |
| 45. | 3.10 | Week 16, 2018 | SF | ChiChi | 20 Rush, 6 Receiving, 1 Rec |
| 47. | 3.00 | Week 06, 2017 | SF | @Was@Was | 21 Rush, 15 Receiving |
| 47. | 3.00 | Week 02, 2017 | SF | @Sea@Sea | 35 Rush, 3 Receiving |
| 49. | 2.90 | Week 05, 2023 | NYG | @Mia@Mia | 21 Rush, 3 Receiving, 1 Rec |
| 50. | 2.50 | Week 14, 2022 | NYG | PhiPhi | 6 Rush, 9 Receiving, 2 Rec |