*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 46.00 | Week 03, 2005 * | SD | NYGNYG | 26 Pass, 192 Rush, 28 Receiving, 4 TD, 1 Fumb |
| 2. | 45.00 | Week 06, 2007 * | SD | OakOak | 198 Rush, 16 Receiving, 4 TD |
| 2. | 45.00 | Week 13, 2002 * | SD | DenDen | 220 Rush, 51 Receiving, 3 TD |
| 4. | 42.00 | Week 08, 2006 | SD | StLStL | 183 Rush, 57 Receiving, 3 TD |
| 5. | 41.00 | Week 11, 2006 * | SD | @Den@Den | 105 Rush, 74 Receiving, 4 TD |
| 6. | 39.00 | Week 10, 2006 * | SD | @Cin@Cin | 104 Rush, 54 Receiving, 4 TD |
| 6. | 39.00 | Week 12, 2005 * | SD | @Was@Was | 184 Rush, 29 Receiving, 3 TD |
| 6. | 39.00 | Week 09, 2005 * | SD | @NYJ@NYJ | 107 Rush, 46 Receiving, 4 TD |
| 9. | 38.00 | Week 17, 2003 | SD | OakOak | 243 Rush, 17 Receiving, 2 TD |
| 10. | 37.00 | Week 09, 2006 | SD | CleCle | 172 Rush, 20 Receiving, 3 TD |
| 10. | 37.00 | Week 06, 2006 * | SD | @SF@SF | 71 Rush, 64 Receiving, 4 TD |
| 12. | 35.00 | Week 06, 2005 | SD | @Oak@Oak | 4 Pass, 140 Rush, 39 Receiving, 3 TD |
| 12. | 35.00 | Week 14, 2003 | SD | @Det@Det | 88 Rush, 148 Receiving, 2 TD |
| 12. | 35.00 | Week 04, 2002 | SD | NENE | 217 Rush, 20 Receiving, 2 TD |
| 15. | 33.00 | Week 04, 2003 | SD | @Oak@Oak | 21 Pass, 187 Rush, 24 Receiving, 2 TD |
| 16. | 32.00 | Week 15, 2006 | SD | KCKC | 199 Rush, 5 Receiving, 2 TD |
| 16. | 32.00 | Week 10, 2003 | SD | MinMin | 162 Rush, 45 Receiving, 2 TD |
| 18. | 31.00 | Week 13, 2007 | SD | @KC@KC | 177 Rush, 20 Receiving, 2 TD |
| 18. | 31.00 | Week 13, 2006 | SD | @Buf@Buf | 178 Rush, 14 Receiving, 2 TD |
| 18. | 31.00 | Week 15, 2003 | SD | GBGB | 51 Rush, 144 Receiving, 2 TD |
| 21. | 30.00 | Week 07, 2002 | SD | @Oak@Oak | 153 Rush, 28 Receiving, 2 TD |
| 21. | 30.00 | Week 03, 2001 | SD | CinCin | 107 Rush, 15 Receiving, 3 TD |
| 23. | 29.00 | Week 14, 2007 | SD | @Ten@Ten | 146 Rush, 27 Receiving, 2 TD |
| 23. | 29.00 | Week 14, 2006 | SD | DenDen | 103 Rush, 9 Receiving, 3 TD |
| 23. | 29.00 | Week 12, 2006 | SD | OakOak | 19 Pass, 109 Rush, 5 Receiving, 3 TD |
| 23. | 29.00 | Week 16, 2004 | SD | @Ind@Ind | 81 Rush, 95 Receiving, 2 TD |
| 27. | 28.00 | Week 04, 2005 | SD | @NE@NE | 134 Rush, 34 Receiving, 2 TD |
| 27. | 28.00 | Week 07, 2003 | SD | @Cle@Cle | 200 Rush, 21 Receiving, 1 TD |
| 29. | 27.00 | Week 04, 2010 | NYJ | @Buf@Buf | 133 Rush, 22 Receiving, 2 TD |
| 29. | 27.00 | Week 17, 2008 | SD | DenDen | 96 Rush, 3 TD |
| 31. | 25.00 | Week 13, 2004 | SD | DenDen | 113 Rush, 17 Receiving, 2 TD |
| 32. | 24.00 | Week 15, 2007 | SD | DetDet | 116 Rush, 7 Receiving, 2 TD |
| 32. | 24.00 | Week 07, 2006 | SD | @KC@KC | 1 Pass, 66 Rush, 72 Receiving, 2 TD, 1 Fumb |
| 32. | 24.00 | Week 02, 2006 | SD | TenTen | 71 Rush, 51 Receiving, 2 TD |
| 35. | 23.00 | Week 08, 2008 | SD | @NO@NO | 105 Rush, 65 Receiving, 1 TD |
| 35. | 23.00 | Week 04, 2008 | SD | @Oak@Oak | 106 Rush, 9 Receiving, 2 TD |
| 35. | 23.00 | Week 11, 2004 | SD | @Oak@Oak | 164 Rush, 9 Receiving, 1 TD |
| 35. | 23.00 | Week 03, 2002 | SD | @Ari@Ari | 91 Rush, 25 Receiving, 2 TD |
| 35. | 23.00 | Week 01, 2001 | SD | WasWas | 113 Rush, 12 Receiving, 2 TD, 1 Fumb |
| 40. | 22.00 | Week 15, 2004 | SD | @Cle@Cle | 111 Rush, - 5 Receiving, 2 TD |
| 40. | 22.00 | Week 12, 2004 | SD | @KC@KC | 46 Rush, 57 Receiving, 2 TD |
| 40. | 22.00 | Week 04, 2004 | SD | TenTen | 147 Rush, 13 Receiving, 1 TD |
| 40. | 22.00 | Week 02, 2004 | SD | NYJNYJ | 87 Rush, 76 Receiving, 1 TD |
| 44. | 21.00 | Week 03, 2011 | NYJ | @Oak@Oak | 38 Rush, 116 Receiving, 1 TD |
| 44. | 21.00 | Week 10, 2009 | SD | PhiPhi | 96 Rush, 2 TD |
| 44. | 21.00 | Week 11, 2007 | SD | @Jac@Jac | 62 Rush, 93 Receiving, 1 TD |
| 44. | 21.00 | Week 04, 2007 | SD | KCKC | 132 Rush, 22 Receiving, 1 TD |
| 44. | 21.00 | Week 16, 2003 | SD | @Pit@Pit | 91 Rush, 8 Receiving, 2 TD |
| 44. | 21.00 | Week 03, 2003 | SD | BalBal | 105 Rush, 51 Receiving, 1 TD |
| 44. | 21.00 | Week 06, 2002 | SD | KCKC | 78 Rush, 78 Receiving, 1 TD |