*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 42.00 | Week 09, 2007 * | Pit | BalBal | 9 Tackles, 1 Assist, 3.5 Sacks, 1 Int, 3 FF, 1 Fum Rcvy, 1 PD |
| 2. | 28.00 | Week 02, 2010 * | Pit | @Ten@Ten | 10 Tackles, 1 Assist, 2.0 Sacks, 2 FF, 1 Fum Rcvy |
| 3. | 24.00 | Week 13, 2008 | Pit | @NE@NE | 7 Tackles, 3 Assists, 2.0 Sacks, 2 FF |
| 3. | 24.00 | Week 04, 2008 | Pit | BalBal | 6 Tackles, 5 Assists, 2.5 Sacks, 1 FF |
| 3. | 24.00 | Week 01, 2008 * | Pit | HouHou | 7 Tackles, 2 Assists, 3.0 Sacks, 1 FF |
| 6. | 23.00 | Week 09, 2011 | Pit | BalBal | 8 Tackles, 3.0 Sacks, 1 FF |
| 6. | 23.00 | Week 05, 2009 * | Pit | @Det@Det | 7 Tackles, 1 Assist, 3.0 Sacks, 1 FF |
| 8. | 22.00 | Week 13, 2015 * | Pit | IndInd | 6 Tackles, 1 Assist, 3.0 Sacks, 1 FF |
| 8. | 22.00 | Week 11, 2010 | Pit | OakOak | 5 Tackles, 2.0 Sacks, 1 Int, 1 FF, 1 PD |
| 10. | 21.00 | Week 06, 2010 | Pit | CleCle | 10 Tackles, 1 Assist, 1.5 Sacks, 1 FF, 1 PD |
| 11. | 19.00 | Week 11, 2008 | Pit | SDSD | 2 Tackles, 2 Assists, 1.0 Sack, 1 Int, 1 FF, 1 PD, 1 Safety |
| 12. | 18.00 | Week 13, 2011 | Pit | CinCin | 5 Tackles, 1 Assist, 3.0 Sacks |
| 13. | 17.00 | Week 09, 2016 | Pit | @Bal@Bal | 6 Tackles, 2.0 Sacks, 1 FF |
| 13. | 17.00 | Week 09, 2008 | Pit | @Was@Was | 7 Tackles, 4 Assists, 1.5 Sacks |
| 15. | 16.00 | Week 17, 2017 | NE | NYJNYJ | 3 Tackles, 2 Assists, 2.0 Sacks, 1 FF |
| 15. | 16.00 | Week 04, 2009 | Pit | SDSD | 5 Tackles, 2.0 Sacks, 1 FF |
| 15. | 16.00 | Week 14, 2008 | Pit | DalDal | 6 Tackles, 3 Assists, 1.0 Sack, 1 FF |
| 15. | 16.00 | Week 10, 2008 | Pit | IndInd | 9 Tackles, 3 Assists, 1.0 Sack |
| 19. | 15.00 | Week 09, 2014 | Pit | BalBal | 4 Tackles, 3 Assists, 2.0 Sacks |
| 19. | 15.00 | Week 17, 2012 | Pit | CleCle | 6 Tackles, 5 Assists, 1.0 Sack |
| 19. | 15.00 | Week 07, 2009 | Pit | MinMin | 6 Tackles, 1 Assist, 2.0 Sacks |
| 22. | 14.00 | Week 13, 2012 | Pit | @Bal@Bal | 6 Tackles, 1 Assist, 1.0 Sack, 1 FF |
| 22. | 14.00 | Week 03, 2011 | Pit | @Ind@Ind | 6 Tackles, 1 Assist, 1.0 Sack, 1 FF |
| 22. | 14.00 | Week 07, 2008 | Pit | @Cin@Cin | 3 Tackles, 2 Assists, 2.0 Sacks, 1 PD |
| 22. | 14.00 | Week 11, 2007 | Pit | @NYJ@NYJ | 6 Tackles, 4 Assists, 1.0 Sack |
| 26. | 13.00 | Week 16, 2014 | Pit | KCKC | 4 Tackles, 3 Assists, 1.5 Sacks |
| 26. | 13.00 | Week 12, 2012 | Pit | @Cle@Cle | 8 Tackles, 1 Assist, 1.0 Sack |
| 26. | 13.00 | Week 12, 2010 | Pit | @Buf@Buf | 5 Tackles, 1 Assist, 1.0 Sack, 1 FF |
| 26. | 13.00 | Week 01, 2010 | Pit | AtlAtl | 4 Tackles, 5 Assists, 1.0 Sack |
| 26. | 13.00 | Week 07, 2007 | Pit | @Den@Den | 9 Tackles, 1.0 Sack |
| 31. | 12.00 | Week 04, 2015 | Pit | BalBal | 5 Tackles, 3 Assists, 1.0 Sack |
| 31. | 12.00 | Week 11, 2012 | Pit | BalBal | 6 Tackles, 2 Assists, 1.0 Sack |
| 31. | 12.00 | Week 05, 2008 | Pit | @Jac@Jac | 3 Tackles, 1 Assist, 1.0 Sack, 1 FF, 1 PD |
| 31. | 12.00 | Week 06, 2005 | Pit | JacJac | 6 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| 35. | 11.00 | Week 16, 2016 | Pit | BalBal | 9 Tackles, 2 Assists |
| 35. | 11.00 | Week 06, 2015 | Pit | AriAri | 3 Tackles, 1 Assist, 1.0 Sack, 1 FF |
| 35. | 11.00 | Week 09, 2010 | Pit | @Cin@Cin | 4 Tackles, 2 Assists, 1.0 Sack, 1 PD |
| 35. | 11.00 | Week 11, 2009 | Pit | @KC@KC | 3 Tackles, 1 Assist, 1.0 Sack, 1 Fum Rcvy |
| 35. | 11.00 | Week 16, 2008 | Pit | @Ten@Ten | 4 Tackles, 3 Assists, 1.0 Sack |
| 35. | 11.00 | Week 10, 2007 | Pit | CleCle | 5 Tackles, 2 FF |
| 35. | 11.00 | Week 08, 2007 | Pit | @Cin@Cin | 3 Tackles, 2 Assists, 1 FF, 1 Fum Rcvy |
| 35. | 11.00 | Week 01, 2007 | Pit | @Cle@Cle | 7 Tackles, 1.0 Sack |
| 35. | 11.00 | Week 05, 2005 | Pit | @SD@SD | 4 Tackles, 1 Assist, 1 Int1 PD |
| 44. | 10.00 | Week 11, 2013 | Cin | CleCle | 3 Tackles, 1 Assist, 1 Int, 1 PD |
| 44. | 10.00 | Week 08, 2013 | Cin | NYJNYJ | 2 Tackles, 4 Assists, 1.0 Sack |
| 44. | 10.00 | Week 06, 2012 | Pit | @Ten@Ten | 4 Tackles, 2 Assists, 1.0 Sack |
| 44. | 10.00 | Week 16, 2010 | Pit | CarCar | 2 Tackles, 3 Assists, 1.0 Sack, 1 PD |
| 44. | 10.00 | Week 15, 2010 | Pit | NYJNYJ | 7 Tackles, 3 Assists |
| 44. | 10.00 | Week 03, 2009 | Pit | @Cin@Cin | 3 Tackles, 2 Assists, 1.0 Sack, 1 PD |
| 44. | 10.00 | Week 17, 2004 | Pit | @Buf@Buf | 1 Tackle, 1 TD, 1 Fum Rcvy |