*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 32.00 | Week 08, 2005 | SD | KCKC | 145 Receiving, 3 TD |
| 2. | 27.00 | Week 02, 2014 | SD | SeaSea | 96 Receiving, 3 TD |
| 3. | 26.00 | Week 04, 2010 | SD | AriAri | 144 Receiving, 2 TD |
| 4. | 24.00 | Week 04, 2009 | SD | @Pit@Pit | 124 Receiving, 2 TD |
| 5. | 23.00 | Week 12, 2009 | SD | KCKC | 118 Receiving, 2 TD |
| 5. | 23.00 | Week 09, 2004 | SD | NONO | 56 Receiving, 3 TD |
| 7. | 22.00 | Week 12, 2007 | SD | BalBal | 105 Receiving, 2 TD |
| 7. | 22.00 | Week 14, 2006 | SD | DenDen | 104 Receiving, 2 TD |
| 9. | 21.00 | Week 05, 2015 | SD | PitPit | 92 Receiving, 2 TD |
| 9. | 21.00 | Week 16, 2014 | SD | @SF@SF | 92 Receiving, 2 TD |
| 9. | 21.00 | Week 08, 2007 | SD | HouHou | 92 Receiving, 2 TD |
| 9. | 21.00 | Week 12, 2004 | SD | @KC@KC | 92 Receiving, 2 TD |
| 9. | 21.00 | Week 05, 2004 | SD | JacJac | 93 Receiving, 2 TD |
| 14. | 20.00 | Week 06, 2012 | SD | DenDen | 81 Receiving, 2 TD |
| 15. | 19.00 | Week 04, 2013 | SD | DalDal | 136 Receiving, 1 TD |
| 16. | 18.00 | Week 05, 2014 | SD | NYJNYJ | 60 Receiving, 2 TD |
| 16. | 18.00 | Week 14, 2011 | SD | BufBuf | 68 Receiving, 2 TD |
| 16. | 18.00 | Week 08, 2010 | SD | TenTen | 123 Receiving, 1 TD |
| 16. | 18.00 | Week 14, 2005 | SD | MiaMia | 123 Receiving, 1 TD |
| 16. | 18.00 | Week 08, 2004 | SD | OakOak | 63 Receiving, 2 TD |
| 21. | 17.00 | Week 12, 2015 | SD | @Jac@Jac | 53 Receiving, 2 TD |
| 21. | 17.00 | Week 08, 2014 | SD | @Den@Den | 54 Receiving, 2 TD |
| 21. | 17.00 | Week 02, 2010 | SD | JacJac | 57 Receiving, 2 TD |
| 21. | 17.00 | Week 05, 2007 | SD | @Den@Den | 113 Receiving, 1 TD |
| 25. | 16.50 | Week 11, 2018 | LAC | DenDen | 80 Receiving, 5 Rec, 1 TD |
| 26. | 16.00 | Week 17, 2011 | SD | @Oak@Oak | 106 Receiving, 1 TD |
| 26. | 16.00 | Week 03, 2010 | SD | @Sea@Sea | 109 Receiving, 1 TD |
| 26. | 16.00 | Week 13, 2009 | SD | @Cle@Cle | 167 Receiving |
| 26. | 16.00 | Week 16, 2008 | SD | @TB@TB | 43 Receiving, 2 TD |
| 26. | 16.00 | Week 01, 2007 | SD | ChiChi | 107 Receiving, 1 TD |
| 26. | 16.00 | Week 11, 2004 | SD | @Oak@Oak | 101 Receiving, 1 TD |
| 32. | 15.00 | Week 16, 2016 | SD | @Cle@Cle | 94 Receiving, 1 TD |
| 32. | 15.00 | Week 09, 2011 | SD | GBGB | 96 Receiving, 1 TD |
| 32. | 15.00 | Week 05, 2010 | SD | @Oak@Oak | 92 Receiving, 1 TD |
| 32. | 15.00 | Week 08, 2008 | SD | @NO@NO | 96 Receiving, 1 TD |
| 32. | 15.00 | Week 13, 2006 | SD | @Buf@Buf | 90 Receiving, 1 TD |
| 32. | 15.00 | Week 03, 2005 | SD | NYGNYG | 92 Receiving, 1 TD |
| 38. | 14.00 | Week 16, 2017 | LAC | @NYJ@NYJ | 81 Receiving, 1 TD |
| 38. | 14.00 | Week 12, 2006 | SD | OakOak | 81 Receiving, 1 TD |
| 40. | 13.00 | Week 09, 2016 | SD | TenTen | 75 Receiving, 1 TD |
| 40. | 13.00 | Week 13, 2010 | SD | OakOak | 73 Receiving, 1 TD |
| 40. | 13.00 | Week 01, 2010 | SD | @KC@KC | 76 Receiving, 1 TD |
| 40. | 13.00 | Week 16, 2009 | SD | @Ten@Ten | 74 Receiving, 1 TD |
| 40. | 13.00 | Week 02, 2007 | SD | @NE@NE | 77 Receiving, 1 TD |
| 40. | 13.00 | Week 06, 2006 | SD | @SF@SF | 78 Receiving, 1 TD |
| 40. | 13.00 | Week 11, 2005 | SD | BufBuf | 77 Receiving, 1 TD |
| 40. | 13.00 | Week 09, 2005 | SD | @NYJ@NYJ | 132 Receiving |
| 40. | 13.00 | Week 07, 2005 | SD | @Phi@Phi | 72 Receiving, 1 TD |
| 40. | 13.00 | Week 15, 2004 | SD | @Cle@Cle | 72 Receiving, 1 TD |
| 50. | 12.00 | Week 10, 2016 | SD | MiaMia | 63 Receiving, 1 TD |