*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 37.00 | Week 12, 2008 | Buf | @KC@KC | 273 Pass, 38 Rush, 4 TD |
| 2. | 30.00 | Week 14, 2007 | Buf | MiaMia | 165 Pass, 2 Rush, 4 TD |
| 3. | 22.00 | Week 01, 2009 | Buf | @NE@NE | 212 Pass, 25 Rush, 2 TD |
| 4. | 21.00 | Week 02, 2009 | Buf | TBTB | |
| 5. | 16.00 | Week 07, 2008 | Buf | SDSD | 261 Pass, 6 Rush, 1 TD |
| 6. | 14.00 | Week 16, 2008 | Buf | @Den@Den | 193 Pass, 10 Rush, 1 TD |
| 6. | 14.00 | Week 03, 2008 | Buf | OakOak | 279 Pass, 9 Rush, 1 TD, 1 Int, 1 Fumb |
| 6. | 14.00 | Week 02, 2008 | Buf | @Jac@Jac | 239 Pass, - 1 Rush, 1 TD, 1 Fumb |
| 6. | 14.00 | Week 01, 2008 | Buf | SeaSea | 215 Pass, - 1 Rush, 1 TD |
| 10. | 13.00 | Week 04, 2008 | Buf | @StL@StL | 197 Pass, 8 Rush, 1 TD, 1 Int, 1 2-Pt |
| 10. | 13.00 | Week 04, 2007 | Buf | NYJNYJ | 234 Pass, - 1 Rush, 1 TD, 1 Int |
| 12. | 12.00 | Week 01, 2010 | Buf | MiaMia | 139 Pass, 12 Rush, 1 TD |
| 12. | 12.00 | Week 09, 2008 | Buf | NYJNYJ | 289 Pass, - 1 Rush, 1 TD, 2 Int, 1 Fumb |
| 12. | 12.00 | Week 16, 2007 | Buf | NYGNYG | 161 Pass, 7 Rush, 2 TD, 3 Int |
| 15. | 11.00 | Week 10, 2009 | Buf | @Ten@Ten | 185 Pass, 4 Rush, 1 TD, 1 Int |
| 15. | 11.00 | Week 11, 2008 | Buf | CleCle | 148 Pass, 7 Rush, 2 TD, 3 Int |
| 17. | 10.00 | Week 17, 2010 | Jac | @Hou@Hou | 140 Pass, 18 Rush, 1 TD, 1 Int |
| 17. | 10.00 | Week 13, 2007 | Buf | @Was@Was | 257 Pass, 4 Rush |
| 19. | 8.00 | Week 05, 2009 | Buf | CleCle | 152 Pass, 40 Rush, 1 Int |
| 20. | 7.00 | Week 04, 2009 | Buf | @Mia@Mia | 192 Pass, 1 TD, 3 Int |
| 20. | 7.00 | Week 08, 2008 | Buf | @Mia@Mia | 227 Pass, 17 Rush, 1 Int, 1 Fumb |
| 22. | 6.00 | Week 17, 2008 | Buf | NENE | 128 Pass, 20 Rush, 1 Fumb |
| 22. | 6.00 | Week 10, 2008 | Buf | @NE@NE | 120 Pass, 1 TD, 2 Int |
| 22. | 6.00 | Week 17, 2007 | Buf | @Phi@Phi | 133 Pass, 17 Rush |
| 25. | 5.00 | Week 03, 2009 | Buf | NONO | 156 Pass, 13 Rush, 1 Int |
| 25. | 5.00 | Week 15, 2007 | Buf | @Cle@Cle | 124 Pass, 12 Rush |
| 25. | 5.00 | Week 05, 2007 | Buf | DalDal | 176 Pass, 6 Rush, 1 Int |
| 28. | 4.00 | Week 13, 2008 | Buf | SFSF | 112 Pass, 5 Rush |
| 28. | 4.00 | Week 07, 2007 | Buf | BalBal | 153 Pass, 1 Int |
| 30. | 3.00 | Week 08, 2007 | Buf | @NYJ@NYJ | 130 Pass, 2 Rush, 1 Int |
| 31. | 2.00 | Week 06, 2010 | Jac | TenTen | 140 Pass, 16 Rush, 2 Int |
| 32. | 1.00 | Week 02, 2010 | Buf | @GB@GB | 102 Pass, 12 Rush, 2 Int |
| 32. | 1.00 | Week 06, 2009 | Buf | @NYJ@NYJ | 43 Pass |
| 32. | 1.00 | Week 03, 2007 | Buf | @NE@NE | 97 Pass, 1 Int |
| 35. | 0.00 | Week 03, 2017 | Oak | @Was@Was | Played, No Stats |
| 35. | 0.00 | Week 02, 2017 | Oak | NYJNYJ | Played, No Stats |
| 35. | 0.00 | Week 01, 2017 | Oak | @Ten@Ten | Played, No Stats |
| 35. | 0.00 | Week 05, 2008 | Buf | @Ari@Ari | 18 Pass |
| 39. | -1.00 | Week 15, 2009 | Buf | NENE | - 1 Pass |