| Pos. | Starters | Team | Points | PPG | Total | Games | Breakdown |
| C | J.T. Realmuto | Phi | 16 | 3.00 | 345 | 7 | 7 TB, 2 RBI, 2 Runs, 2 SB, 3 BB |
| 1B (2B,SS) | Jake Cronenworth | SD | 7 | 3.28 | 450 | 3 | 4 TB, 1 RBI, 1 Run, 1 BB |
| 2B (OF) | Brandon Lowe | TB | 13 | 3.58 | 476 | 4 | 6 TB, 3 RBI, 2 Runs, 2 BB |
| SS (2B) | Marcus Semien | Tor | 47(54) | 4.10 | 586 | 8 | 27 TB, 12 RBI, 8 Runs, 1 SB, 6 BB |
| 3B | Manny Machado | SD | 14 | 3.57 | 479 | 5 | 6 TB, 1 RBI, 3 Runs, 1 SB, 3 BB |
| OF | Robbie Grossman | Det | 31 | 3.36 | 464 | 6 | 16 TB, 4 RBI, 6 Runs, 1 SB, 4 BB |
| OF (DH) | Austin Meadows | TB | 9 | 3.46 | 443 | 5 | 5 TB, 2 RBI, 2 Runs |
| OF | Bryan Reynolds | Pit | 20 | 3.49 | 489 | 6 | 9 TB, 4 RBI, 3 Runs, 4 BB |
| DH (OF) | Akil Baddoo | Det | 15 | 3.09 | 318 | 6 | 8 TB, 4 Runs, 3 BB |
| Pos. | 1st Backup | Team | Points | PPG | Total | Games | Breakdown |
| C | Mitch Garver | Min | DNP | 2.97 | 181 | 0 | Did Not Play |
| 1B | Bobby Bradley | Cle | 4(5) | 2.98 | 173 | 5 | 3 TB, 2 RBI |
| 2B | Cesar Hernández | ChA | 6(13) | 2.91 | 390 | 6 | 6 TB, 3 RBI, 3 Runs, 1 BB |
| SS | Miguel Rojas | Mia | 0(8) | 2.81 | 331 | 5 | 4 TB, 2 RBI, 2 Runs |
| 3B (2B) | Eduardo Escobar | Mil | 11(33) | 3.32 | 425 | 6 | 16 TB, 8 RBI, 6 Runs, 3 BB |
| OF | Austin Hays | Bal | 20(36) | 3.05 | 339 | 7 | 21 TB, 9 RBI, 5 Runs, 1 BB |
| DH (1B) | Jesus Aguilar | Mia | DNP | 2.99 | 392 | 0 | Did Not Play |
| Pos. | 2nd Backup | Team | Points | PPG | Total | Games | Breakdown |
| 3B | Giovanny Urshela | NYA | 0(3) | 2.41 | 234 | 6 | 3 TB |
| OF (DH) | George Springer | Tor | 0(13) | 4.03 | 238 | 4 | 7 TB, 2 RBI, 2 Runs, 2 BB |
| DH (3B) | Patrick Wisdom | ChN | 1(6) | 2.99 | 284 | 6 | 5 TB, 1 Run |
| Pos. | Bench | Team | Points | PPG | Total | Games | Breakdown |
| OF | Wil Myers | SD | 8 | 2.67 | 345 | 5 | 2 TB, 1 RBI, 2 Runs, 3 BB |
| Pitching Staff Alignment | |||||||
| 10 Starts, 0 Relievers | |||||||
| Pos. | Pitching Order | Team | Points | PPG | Total | Games | Breakdown |
| 1st SP | Anthony DeSclafani | SF | 3 | 12.93 | 349 | 1 | 3 Non W/S+ |
| 2nd SP | Brandon Woodruff | Mil | 6 | 14.19 | 383 | 1 | 6 Non W/S+ |
| 3rd SP | Lance McCullers | Hou | 38 | 13.76 | 344 | 2 | 2 Wins, 18 W/S+ |
| 4th SP | Max Fried | Atl | 24 | 13.68 | 342 | 2 | 24 Non W/S+ |
| 5th SP | Marco Gonzales | Sea | 22 | 12.33 | 259 | 1 | 1 Win, 12 W/S+ |
| 6th SP | Sean Manaea | Oak | 22 | 12.11 | 339 | 1 | 1 Win, 12 W/S+ |
| 7th SP (RP) | Cal Quantrill | Cle | 22 | 7.84 | 290 | 1 | 1 Win, 12 W/S+ |
| 8th SP | Taijuan Walker | NYN | 3 | 10.04 | 271 | 1 | 3 Non W/S+ |
| 9th SP | Tarik Skubal | Det | 0(12) | 9.75 | 273 | 2 | 12 Non W/S+ |
| 10th SP | Lance Lynn | ChA | 0(15) | 14.60 | 365 | 1 | 15 Non W/S+ |
| 1st RP | Liam Hendriks | ChA | 0(27) | 8.51 | 519 | 3 | 2 Saves, 4 W/S+, 3 Non W/S+ |
| Hit=214 Pit=140 Total=354 | |||||||
| Pos. | Injured List | Team | Points | PPG | Total | Games | Breakdown |
| SP | Chris Bassitt | Oak | DNP | 14.24 | 356 | 0 | Did Not Play |
| SP | Dakota Hudson | StL | DNP | 0.00 | 0 | 0 | Did Not Play |
| OF | Marcell Ozuna | Atl | DNP | 2.77 | 133 | 0 | Did Not Play |